Autopsy report · NCT06304740

Safety and Pharmacokinetics of Subcutaneous Dose of IMG-007 in Healthy Participants

“Cohorts 1 and 2 were completed. Cohort 3 was cancelled because it was no longer necessary based on information from another study. No safety concerns were noted.”

The sponsor’s own words in the registry.

Life of this trial

• Ran for about 6 months before it stopped.
• 16 participants enrolled.
• No results are posted on the registry.

Vital statistics

Status

Terminated

Phase

Phase 1

Sponsor

Inmagene LLC

Sponsor type

Industry

Conditions

Healthy Volunteers

Interventions

IMG-007; Placebo

Participants

16

Sites

1

Countries

Australia

Trials that died the same way

• Tai Chi and Wellness Education for Older Veterans
  “The study was stopped after completing 2 cohorts instead of the intended 3 cohorts. This was due to logistical issues and budget-related issues (timing of being able to spend the funds).” (73% match in meaning)
• Study to Evaluate the Safety of AT2220 (Duvoglustat) in Pompe Disease
  “Per protocol, 3 sequential dose cohorts were planned. Study discontinued by Sponsor based upon serious adverse events in first 2 of 3 participants in Cohort 1.” (71% match in meaning)
• A Study of Isatuximab-based Therapy in Participants With Lymphoma
  “Study was stopped after interim analysis for all 4 cohorts with results either not fulfilling the pre-planned interim analysis criteria or fulfilling the criteria but as per sponsor decision. It was not due to any safety concern” (70% match in meaning)
• Study of TAK-071 in Healthy Participants and Participants With Mild Cognitive Impairment/Mild Alzheimer Disease and Relative Bioavailability (BA) and Food Effect of TAK-071 in Healthy Participants
  “Terminated prematurely as data from cohort no longer needed due to indication change.” (70% match in meaning)
• A Study of De-immunized DI-Leu16-IL2 Administered Subcutaneously in Participants With B-cell NHL
  “Clinical benefit was noted in the earlier portion of the trial; hence, participants were not enrolled in 2 expansion cohorts and the study was terminated early.” (69% match in meaning)

Look deeper

• The official registry record (the source of truth)
• Record history: every change the sponsor made
• Open it in the database

Everything here comes from the current ClinicalTrials.gov record. The timeline uses the record’s dates; dates marked planned are the sponsor’s plans. The cause of death is an automatic, unverified label. This is research information, not medical advice.