Healthy Volunteers

Why trials studying Healthy Volunteers stopped, in this sample of ClinicalTrials.gov.

22 stopped trials with a clear reason; 86% ended for non-scientific reasons.

Trials

• Persistence of Oral DNA Adducts in Smokers and Vapers
  NCT06983392 · WITHDRAWN · funding business
  “No longer funded and not moving forward”
• A Study to Learn About the Study Medicine Called PF-07258669 in Older Adults Including Those at Risk of Malnutrition
  NCT07086664 · TERMINATED · funding business
  “The study was prematurely discontinued due to a business decision. The decision to terminate the study is not related to a safety concern.”
• Evaluation of the Biomechanics of Crowding and the Energetic Cost of Endurance Runners Unilateral Transtibial Amputees.
  NCT06948695 · TERMINATED · slow accrual
  “Difficulties in enrolling patients”
• Single and Multiple Ascending Dose Study of AMG 378 in Healthy Participants
  NCT06910709 · TERMINATED · funding business
  “Business Decision”
• A Study of RBI-4000 in Healthy Participants
  NCT06048770 · TERMINATED · funding business
  “Strategic business decision (not related to safety, efficacy, or quality)”
• The Effect of Violet Device Dosed Ultra Violet-C Light (UV-C) Exposure on Healthy Hand Skin
  NCT05313555 · TERMINATED · funding business
  “The sponsoring company closed unexpectedly and was unable to continue to support the study.”
• Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of CHK-336 in Healthy Volunteers
  NCT05367661 · TERMINATED · funding business
  “Sponsor decision”
• Study of Safety, Tolerability, and Pharmacokinetics of INE963 in Healthy Participants
  NCT04896632 · TERMINATED · funding business
  “Sponsor's decision.”
• Bioavailability and Food Effect Study of Two Formulations of TAK-906
  NCT04831502 · WITHDRAWN · funding business
  “Business decision”
• Pharmacodynamic Study of BIIB095 and BIIB074 in Healthy Participants and Participants With Painful Diabetic Polyneuropathy
  NCT04106050 · WITHDRAWN · funding business
  “Sponsor Decision”
• Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of CC-97489 in Healthy Adult Participants
  NCT05099822 · TERMINATED · funding business
  “Business objectives changed.”
• Cannabis Effects on Electroencephalography
  NCT04316598 · TERMINATED · logistics pi
  “Terminated by the sponsor in the context of COVID-19 pandemia”
• Healthy Volunteer Study to Evaluate the Impact of Various Common Interventions on Venous Pressure Signal Captured by PIVA
  NCT04324593 · TERMINATED · logistics pi
  “Terminated due to COVID-19”
• A Study With [18F]MNI-1054 to Determine Lysine -Specific Demethylase 1A (LSD1) Brain Enzyme Occupancy of TAK-418 After Single-Dose Oral Administration in Healthy Participants
  NCT04202497 · TERMINATED · logistics pi
  “Study was prematurely terminated because of administrative reasons.”
• HI Study to Assess and Compare the Pharmacokinetic Parameters of MD1003 in Hepatic Impaired Patients and Healthy Subjects
  NCT04252417 · TERMINATED · futility
  “Due to other Phase 3 trial failure to meet primary endpoint”
• RI Study to Assess and Compare the Pharmacokinetic Parameters of MD1003 in Renal Impaired Patients and Healthy Subjects
  NCT04252430 · TERMINATED · futility
  “Due to other phase 3 trial failure to meet primary endpoint”
• Novel PET Radioligand as an Inflammatory Biomarker in Musculoskeletal Conditions
  NCT03912428 · TERMINATED · slow accrual
  “due to difficulty with participant recruitment and data futility”
• Effects of GSK2798745 on Alveolar Barrier Disruption in a Segmental Lipopolysaccharide (LPS) Challenge Model
  NCT03511105 · TERMINATED · futility
  “Study terminated due to low probability of achieving a positive outcome on the primary endpoint.”
• Study of TAK-071 in Healthy Participants and Participants With Mild Cognitive Impairment/Mild Alzheimer Disease and Relative Bioavailability (BA) and Food Effect of TAK-071 in Healthy Participants
  NCT02769065 · TERMINATED · funding business
  “Terminated prematurely as data from cohort no longer needed due to indication change.”
• A Safety, Tolerability and Pharmacokinetics Study of TransCon Treprostinil in Healthy Adult Male Volunteers
  NCT03803163 · TERMINATED · slow accrual
  “Discontinued early due to local tolerance expectations not being met.”
• DHB Supplement Interaction Study
  NCT02257879 · WITHDRAWN · funding business
  “due to constraints with collaborator and subject matter expert, recruitment was unable to begin”
• MLN3126 Single Rising Dose Study
  NCT02447458 · TERMINATED · regulatory
  “Site non-compliance to GCP (No safety concerns. See detailed description)”

Reasons are labeled automatically and are unverified. See the methodology. This is research information, not medical advice. Search the full database.