Autopsy report · NCT00937664

Safety and Tolerability Study of AZD7762 in Combination With Gemcitabine

“Termination of the study was made after a full review of program data and assessment of the current risk-benefit profile.”

The sponsor’s own words in the registry.

Life of this trial

• Ran for about 1 year 7 months before it stopped.
• 24 participants enrolled.
• No results are posted on the registry.

Vital statistics

Status

Terminated

Phase

Phase 1

Sponsor

AstraZeneca

Sponsor type

Industry

Conditions

Cancer; Solid Tumors; Advanced Solid Malignancies

Interventions

AZD7762; gemcitabine

Participants

24

Sites

1

Countries

Japan

Trials that died the same way

• A Pharmacokinetic Analysis of Posaconazole in Lung Transplant Recipients (MK-5592-105)
  “Study terminated due to an unfavorable risk-benefit analysis” (80% match in meaning)
• A Clinical Study to Test How Effective and Safe GLPG1690 is for Subjects With Idiopathic Pulmonary Fibrosis (IPF) When Used Together With Standard of Care
  “The benefit-risk profile no longer supports continuing the study” (75% match in meaning)
• PROPEL - A Prospective Observational Patient Registry to Evaluate ENPP1 and ABCC6 Deficiency
  “The study was terminated by the sponsor prior to planned completion based on a review of the data across indications and overall program considerations. Study termination was not related to participant safety.” (73% match in meaning)
• Study of AZD0466 Monotherapy or in Combination in Patients With Advanced Haematological Malignancies
  “Trial terminated based on benefit-risk profile assessment” (73% match in meaning)
• PFC Sigma Fixed and Mobile Knee Study
  “The study was terminated at the point the primary endpoint and early milestones were reached and because long term outcomes were available from other sources” (72% match in meaning)

Look deeper

• The official registry record (the source of truth)
• Record history: every change the sponsor made
• Open it in the database

Everything here comes from the current ClinicalTrials.gov record. The timeline uses the record’s dates; dates marked planned are the sponsor’s plans. The cause of death is an automatic, unverified label. This is research information, not medical advice.