Cancer

Why trials studying Cancer stopped, in this sample of ClinicalTrials.gov.

55 stopped trials with a clear reason; 98% ended for non-scientific reasons.

Trials

• Immune Reconstitution Monitoring and Pneumococcal Vaccination in Patients Treated With CAR-T Cells
  NCT07071909 · WITHDRAWN · funding business
  “Funding unavailable”
• A Multicomponent Technology Supported Care Delivery for Older Patients With Hematologic Malignancies (The M-Tech Study)
  NCT05153447 · WITHDRAWN · funding business
  “Unable to obtain funding”
• Long-Term Follow-Up Safety Study of Subjects Treated with SynKIR-110 in Cancer Studies
  NCT06377202 · WITHDRAWN · safety
  “The study is being withdrawn and replaced by a new multicenter LTFU Basket Study, designed to monitor the long-term safety of all SynKIR CAR T cell products. This updated study will include all participants who have been treated with Verismo Therapeu”
• Behavioral Coaching Intervention (Laguna Health) for Patients With Cancer
  NCT06004141 · TERMINATED · funding business
  “Terminated due to withdrawal of funding from Sponsor (Laguna Health)”
• Training of Arms to Reduce Pain With Peripheral Venous Catheter
  NCT05716217 · TERMINATED · slow accrual
  “Changes in provision of chemotherapy have made it impossible to recruit patients according to the protocol”
• ImmunoCARE: Rapid, Accurate COVID Testing to Reduce Hospitalization of Immunocompromised Individuals
  NCT05655546 · TERMINATED · regulatory
  “On May 13, 2024, the FDA released a communication that Cue Health tests should no longer be used.”
• Impact of Relaxing Visual Immersion on Anxiety During Anti-cancer Treatment.
  NCT04528238 · WITHDRAWN · logistics pi
  “following the covid health crisis the study has not begun”
• TT-816 As Monotherapy or in Combination with a PD-1 Inhibitor in Patients with Advanced Cancers (SEABEAM) (MK3475-E88)
  NCT05525455 · TERMINATED · funding business
  “Company operational decision. Decision to stop study is not due to safety or efficacy concerns.”
• Study of the Safety, Tolerability and Efficacy of Metabolic Combination Treatments on Cancer
  NCT02201381 · WITHDRAWN · slow accrual
  “Prospective recruitment not possible”
• Study of Combined Decompressive Spine Radiosurgery and Pembrolizumab
  NCT05204290 · TERMINATED · slow accrual
  “Low accruals”
• Mirtazapine in Cancer-related Poly-symptomatology
  NCT04763135 · TERMINATED · slow accrual
  “difficulties in recruiting”
• A Supportive Care Intervention for Older Caregivers of Older Adults with Advanced Cancer
  NCT05244915 · TERMINATED · slow accrual
  “Study has been closed to accrual earlier than anticipated and will not resume.”
• GIST in Hematopoietic Stem Cell Transplantation/Bone Marrow Transplantation
  NCT03959046 · WITHDRAWN · logistics pi
  “The study has been withdrawn due to delays caused by COVID-19 and practical barriers to conducting the study.”
• Immune Checkpoint Blockade Therapy Using 18F-FLT PET/CT
  NCT04271436 · WITHDRAWN · slow accrual
  “Low accrual”
• Pilot RCT Feasibility Study: Cancer and T2D
  NCT04468243 · TERMINATED · slow accrual
  “Slow Accrual”
• Study of 68GaNOTA-Anti-MMR-VHH2 in Oncological Lesions, Cardiovascular Atherosclerosis, Syndrome With Abnormal Immune Activation and sarcoïdosis
  NCT04758650 · TERMINATED · slow accrual
  “Delay in recruitment”
• Suubi4Cancer: Improving Access to Pediatric Cancer Services and Treatment Adherence Among Children Living With HIV/AIDS
  NCT03916783 · WITHDRAWN · slow accrual
  “We implemented Aims 1 and 2, but did not have a sufficient sample size to carry out the clinical trial portion”
• Screening of Cancer Patients to Assess Impact of COVID-19
  NCT04373005 · TERMINATED · logistics pi
  “Participants were not testing positive for COVID-19 and were not returning onsite for visits.”
• A Study to Determine Safety, Tolerability, Pharmacokinetics, and Recommended Phase 2 Dose (RP2D) of Intravenous ABBV-184 in Adult Participants With Previously Treated Cancers
  NCT04272203 · TERMINATED · funding business
  “Strategic considerations”
• Vopratelimab (JTX-2011) Alone and in Combination With Anti-Programmed Cell Death Protein 1 (PD-1) or Anti-Cytotoxic T-Lymphocyte Antigen 4 (CTLA-4) in Subjects With Advanced and/or Refractory Solid Tumors
  NCT04319224 · TERMINATED · funding business
  “Sponsor decision to discontinue providing study drug to patients who have been on study treatment for more than two years”
• Implementation of a Tool to Identify Social Weaknesses in the Cancer Care Pathway
  NCT04015895 · TERMINATED · slow accrual
  “low inclusion rates”
• Nutrition Health Literacy of Cancer Patients and Their Support Networks.
  NCT03978312 · TERMINATED · slow accrual
  “Recruitment was due to be extended (March 20) due to slow initial recruitment however was terminated early due to corresponding arrival of COVID-19 to UK. (16 recruited to cultural and linguistic phase and 42 to observational cohort)”
• Symptom Screening With Targeted Early Palliative Care (STEP) Versus Usual Care for Patients With Advanced Cancer
  NCT03987906 · TERMINATED · logistics pi
  “COVID-19 pandemic”
• A Study to Evaluate Sotigalimab (APX005M) in Subjects With Unresectable or Metastatic Melanoma
  NCT04337931 · TERMINATED · funding business
  “Business decision (not due to safety reason).”
• The Role of Emotions and Regulatory Focus in Decision Making That Involves Risk Tradeoffs
  NCT02874053 · WITHDRAWN · logistics pi
  “PI left the NIH”
• A Phase 3, Randomized, Double-blind, Placebo-controlled Study For Subjects With Locally-advanced Unresectable or Metastatic Synovial Sarcoma (V943-003, IMDZ-04-1702)
  NCT03520959 · TERMINATED · funding business
  “Study was terminated due to sponsor's decision.”
• Group Metacognitive Therapy for Anxiety and Depression in Cancer Survivors
  NCT03424512 · TERMINATED · logistics pi
  “Covid-19 halted study, reorganisation of the clincial service and staff leaving posts made recruitement to a group unfeasible”
• Role of Virtual Reality (VR) in Patients With Sickle Cell Disease (SCD)
  NCT03387033 · TERMINATED · funding business
  “enrollment closed due to lack of funding”
• Evaluating the CAREchart@Home™ Program for Enhancing After-hours Cancer Care
  NCT04232709 · TERMINATED · funding business
  “Due to unforeseen circumstances, the funder decided to discontinue all funding.”
• Consolidation Therapy in Patients With Metastatic Solid Malignancies
  NCT02705703 · WITHDRAWN · funding business
  “Sponsor decision to discontinue study.”
• Collection of Malignant Ascites, Pleural Fluid, and Blood From People With Solid Tumors
  NCT03189108 · TERMINATED · logistics pi
  “PI left NIH”
• Impact of Early Implementation of Narrative Medicine Techniques on Patient Centered Attitudes of Medical Students
  NCT03041571 · WITHDRAWN · logistics pi
  “PI is no longer with UF. No New PI assigned to date.”
• Durvalumab in Combination With Tremelimumab in Subjects With Advanced Rare Solid Tumors
  NCT02938793 · TERMINATED · slow accrual
  “poor enrollment likely due to expanded availability of immunotherapy for patients”
• Tolerability, Safety, and Feasibility of Naloxegol in Patients With Cancer and OIC (Opioid Induced Constipation)
  NCT02839889 · TERMINATED · slow accrual
  “The study was stopped due to challenges recruiting eligible patients.”
• Medical Treatment Decision Making Using Adaptive Conjoint Analysis
  NCT02608307 · TERMINATED · slow accrual
  “Slow accrual and COVID-19 restrictions”
• Adaptated Physical Activity During Chemotherapy: Evaluation of the Psychological, Physiological and Biological Impact
  NCT02785341 · TERMINATED · slow accrual
  “Insufficient recruitment”
• Navigated Early Survivorship Transition in Patients With Newly Diagnosed Cancer and Their Caregivers
  NCT02440737 · TERMINATED · slow accrual
  “Slow accrual”
• A Phase I/II Study of Ganetespib in Combination With Doxorubicin
  NCT02261805 · TERMINATED · funding business
  “Company terminated drug support”
• In Vitro Fertilization and Pregnancy After Use of Chemotherapy
  NCT00520364 · TERMINATED · logistics pi
  “PI left the Institution.”
• Influenza Vaccination in Cancer Patients
  NCT02213432 · TERMINATED · slow accrual
  “Insufficient enrollment”
• Thoracal Radiotherapy and Tarceva
  NCT02714530 · TERMINATED · slow accrual
  “Slow accrual”
• A Study to Evaluate Foretinib in Subjects With Non-Small-Cell Lung Cancer
  NCT02034097 · WITHDRAWN · funding business
  “GSK has decided to terminate the Product Development of foretinib and conclude our Development Agreement with Exelixis”
• Self-help Program Via Internet for Adolescents With Cancer
  NCT01510236 · WITHDRAWN · slow accrual
  “a feasibility study showed low recruitment and adherence”
• Oral Ketamine in the Treatment of Depression and Anxiety in Patients With Cancer
  NCT01680172 · TERMINATED · slow accrual
  “Slow enrollment”
• A Phase I Study of OSI-906 in Combination With Pemetrexed in Advanced Solid Tumor Malignancies
  NCT01567384 · WITHDRAWN · funding business
  “The sponsor withdrew support for the study before any patients were enrolled.”
• Excision Limits of Oral Cavity Tumor by Narrow Band Imaging
  NCT01198119 · TERMINATED · slow accrual
  “lack of recruitment”
• Interrogation of Wnt, Notch and Hedgehog Activity in Primary Tumor Samples
  NCT02006550 · TERMINATED · funding business
  “Lack of Resources and Personnel”
• Pilot Study of Biomarkers for Radiation Therapy
  NCT01050725 · SUSPENDED · funding business
  “On hold: pending grant funding for further enrollment”
• Genetic Susceptibility and Risk of Second Cancers in Patients Who Have Undergone Stem Cell Transplant for Cancer
  NCT00949052 · TERMINATED · slow accrual
  “Low accrual”
• A Trial of ALB 109564(a) in Subjects With Advanced Solid Tumors
  NCT00724100 · TERMINATED · funding business
  “Sponsor's decision”
• Cyclophosphamide and Cryoablation in Treating Patients With Advanced or Metastatic Epithelial Cancer
  NCT00499733 · TERMINATED · logistics pi
  “The study was terminated per PI decision.”
• A Study to Evaluate the Effectiveness and Safety of CG5503 (Tapentadol) in the Treatment of Chronic Tumor Related Pain Compared With Placebo and Morphine
  NCT00505414 · TERMINATED · manufacturing supply
  “Recall of rescue medication, alternative rescue medication availability issues.”
• Tinzaparin for Primary Treatment and Extended Secondary Prophylaxis of Venous Thromboembolism in Patients With Cancer
  NCT00981903 · TERMINATED · manufacturing supply
  “Tinzaparin will no longer be available in the United States”
• A Study of Docetaxel in Combination With Capecitabine in Stomach and Esophagus Cancers
  NCT00177255 · TERMINATED · funding business
  “Roche has withdrawn support”
• Natrecor in Pulmonary Hypertension
  NCT00075179 · TERMINATED · slow accrual
  “Low accrual.”

Reasons are labeled automatically and are unverified. See the methodology. This is research information, not medical advice. Search the full database.