Autopsy report · NCT06302439

PROPEL - A Prospective Observational Patient Registry to Evaluate ENPP1 and ABCC6 Deficiency

“The study was terminated by the sponsor prior to planned completion based on a review of the data across indications and overall program considerations. Study termination was not related to participant safety.”

The sponsor’s own words in the registry.

Life of this trial

• Registered 5 months before it started.
• Ran for about 2 years 1 month before it stopped.
• 54 participants enrolled.
• No results are posted on the registry.

Vital statistics

Status

Terminated

Sponsor

Inozyme Pharma

Sponsor type

Industry

Conditions

Ectonucleotide Pyrophosphatase/Phosphodiesterase 1 Deficiency; ATP-Binding Cassette Subfamily C Member 6 Deficiency

Interventions

No Intervention for this observational study

Participants

54

Sites

14

Countries

Canada, Germany, Italy, Japan, Oman, Spain, Turkey (Türkiye), United Kingdom, United States

Trials that died the same way

• An Evaluation of the Erchonia Laser As a Non-Invasive Treatment to Improve the Appearance of Skin Laxity
  “The study was terminated early due to sponsor decision unrelated to safety or efficacy findings” (88% match in meaning)
• Study of Ataluren (PTC124) in Hemophilia A and B
  “Study was terminated early due to Sponsor decision and not reflective of adverse safety findings.” (87% match in meaning)
• Colorectal Lesion Evaluation and Appropriate Resolution (CLEAR) Study
  “Study terminated per sponsor decision due to operational reasons. The termination was not a result of any participant safety concerns.” (85% match in meaning)
• Study of Obeldesivir to Treat Children With Respiratory Syncytial Virus (RSV) Infection
  “Study was terminated by Sponsor; the decision was not due to any safety findings.” (83% match in meaning)
• A Study to Assess Recurrence of Actinic Keratosis in Participants Treated With Methyl Aminolevulinate Hydrochloride Cream or Vehicle Cream Who Achieved Complete Response to Treated Lesions in Earlier Study
  “The study was terminated early as per Sponsor's decision” (83% match in meaning)

Look deeper

• The official registry record (the source of truth)
• Record history: every change the sponsor made
• Open it in the database

Everything here comes from the current ClinicalTrials.gov record. The timeline uses the record’s dates; dates marked planned are the sponsor’s plans. The cause of death is an automatic, unverified label. This is research information, not medical advice.