Autopsy report · NCT00947193

Study of Ataluren (PTC124) in Hemophilia A and B

“Study was terminated early due to Sponsor decision and not reflective of adverse safety findings.”

The sponsor’s own words in the registry.

Life of this trial

• Registered 3 months before it started.
• Ran for about 1 year 11 months before it stopped.
• 13 participants enrolled.
• Results were posted on the registry 8 years 10 months after it ended.

Vital statistics

Status

Terminated

Phase

Phase 2

Sponsor

PTC Therapeutics

Sponsor type

Industry

Conditions

Hemophilia A; Hemophilia B

Interventions

Ataluren

Participants

13

Sites

13

Countries

Canada, France, Italy, United States

Trials that died the same way

• An Evaluation of the Erchonia Laser As a Non-Invasive Treatment to Improve the Appearance of Skin Laxity
  “The study was terminated early due to sponsor decision unrelated to safety or efficacy findings” (93% match in meaning)
• Study of Obeldesivir to Treat Children With Respiratory Syncytial Virus (RSV) Infection
  “Study was terminated by Sponsor; the decision was not due to any safety findings.” (90% match in meaning)
• A Study to Assess Recurrence of Actinic Keratosis in Participants Treated With Methyl Aminolevulinate Hydrochloride Cream or Vehicle Cream Who Achieved Complete Response to Treated Lesions in Earlier Study
  “The study was terminated early as per Sponsor's decision” (88% match in meaning)
• A Study of Lorcaserin as Adjunctive Treatment in Participants With Dravet Syndrome
  “The study was terminated by Sponsor and the decision was not due to any safety or efficacy reasons.” (88% match in meaning)
• Colorectal Lesion Evaluation and Appropriate Resolution (CLEAR) Study
  “Study terminated per sponsor decision due to operational reasons. The termination was not a result of any participant safety concerns.” (87% match in meaning)

Look deeper

• The official registry record (the source of truth)
• Record history: every change the sponsor made
• Open it in the database

Everything here comes from the current ClinicalTrials.gov record. The timeline uses the record’s dates; dates marked planned are the sponsor’s plans. The cause of death is an automatic, unverified label. This is research information, not medical advice.