Autopsy report · NCT05808101

Gut Microbiome and Depression

“Change in PI and lack of personnel available to complete futher enrollment”

The sponsor’s own words in the registry.

Life of this trial

• Registered 4 months after it had already started.
• Ran for about 2 years 9 months before it stopped.
• 51 participants enrolled.
• No results are posted on the registry.

Vital statistics

Status

Terminated

Sponsor

Washington University School of Medicine

Sponsor type

University, hospital or other

Conditions

Multiple Sclerosis; Depression

Interventions

Neuro-QoL T-score determination

Participants

51

Sites

1

Countries

United States

Trials that died the same way

• The Evaluation of the Roles of New Cardiac Imaging in Patients With Chest Pain
  “PI departure from institution + Enrollment Challenges” (79% match in meaning)
• Use of a Loading Dose of Vancomycin in Pediatric Dosing
  “PI leaving institution, slow enrollment” (73% match in meaning)
• Phase II Trial of Lurbinectedin Combined With Avelumab as Switch Maintenance Firstline Therapy
  “PI Decision based on no enrollment” (72% match in meaning)
• The Effect of Selenium Supplementation Among Pediatric Patients With Burns
  “Due to a shift in primary responsibilities, the PI was not longer able to enroll subjects.” (71% match in meaning)
• Understanding the Metabolic and Functional Derangement of Primary Mitral Regurgitation: a Feasibility Study Using Carbon 11(C-11) Acetate Cardiac Positron Emission Tomography Magnetic Resonance Imaging (PET-MRI)
  “lack of recruitment and PI departure” (71% match in meaning)

Look deeper

• The official registry record (the source of truth)
• Record history: every change the sponsor made
• Open it in the database

Everything here comes from the current ClinicalTrials.gov record. The timeline uses the record’s dates; dates marked planned are the sponsor’s plans. The cause of death is an automatic, unverified label. This is research information, not medical advice.