Autopsy report · NCT05545319

A Study to Learn About the Medicine Called Nirmatrelvir Used in Combination With Ritonavir in People With Weakened Immune Systems or at Increased Risk for Poor Outcomes Who Are Hospitalized Due to Severe COVID-19

“Termination due to challenges related to the operational feasibility of the study, taking into account the current epidemiology and declining hospitalization rates for severe COVID-19.”

The sponsor’s own words in the registry.

Life of this trial

• Withdrawn before it enrolled anyone. Its dates are the sponsor's plans, not events that happened.

Vital statistics

Status

Withdrawn

Phase

Phase 2

Sponsor

Pfizer

Sponsor type

Industry

Conditions

Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2); Coronavirus Disease 2019 (COVID-19); Immunocompromised; Hospitalization; Child, Hospitalized

Interventions

Nirmatrelvir; Ritonavir; Placebo for nirmatrelvir

Participants

0

Sites

11

Countries

Bulgaria, United States

Trials that died the same way

• Effects of Community-center Based Dietary Intervention on Frailty Prevention and Regression in the Elderly.
  “Due to the impacts of COVID-19, the study had to terminate.” (83% match in meaning)
• Acceptability, Feasibility and Safety of a Yoga Program for Chronic Pain in Sickle Cell Disease
  “Study terminated due to COVID-19 pandemic.” (80% match in meaning)
• A Phase I Clinical Study for Evaluating the Safety and Efficacy of MASCT-I in Patients With Advanced Solid Tumors
  “The study was terminated early due to the COVID-19 pandemic and sponsor's funding constraints, based on promising preliminary safety and efficacy data.” (79% match in meaning)
• Study to Evaluate the Efficacy and Safety of FX006 in Patients With Glenohumeral Osteoarthritis or Shoulder Adhesive Capsulitis
  “The study was terminated prematurely due to the COVID-19 pandemic creating uncertainty impacting trial progress and costs.” (79% match in meaning)
• Optune Device - TT Field Plus Nivolumab and Ipilimumab for Melanoma With Brain Metastasis
  “The study was terminated early on 03/09/2022 due to low accrual during the COVID-19 pandemic.” (78% match in meaning)

Look deeper

• The official registry record (the source of truth)
• Record history: every change the sponsor made
• Open it in the database

Everything here comes from the current ClinicalTrials.gov record. The timeline uses the record’s dates; dates marked planned are the sponsor’s plans. The cause of death is an automatic, unverified label. This is research information, not medical advice.