Autopsy report · NCT03034304

A Phase I Clinical Study for Evaluating the Safety and Efficacy of MASCT-I in Patients With Advanced Solid Tumors

“The study was terminated early due to the COVID-19 pandemic and sponsor's funding constraints, based on promising preliminary safety and efficacy data.”

The sponsor’s own words in the registry.

Life of this trial

• Registered 2 months before it started.
• Ran for about 6 years 9 months before it stopped.
• 105 participants enrolled.
• No results are posted on the registry.

Vital statistics

Status

Terminated

Phase

Phase 1

Sponsor

HRYZ Biotech Co.

Sponsor type

Industry

Conditions

Advanced Solid Tumors

Interventions

MASCT-I; Ifosfamide; PD1 antibody; Adriamycin; Gemcitabine; Cisplatin

Participants

105

Sites

9

Countries

China

Trials that died the same way

• A Study to Assess the Therapeutic Effect and Safety of Adjunctive AKST4290 in Subjects With Bullous Pemphigoid
  “The study was prematurely terminated by the Sponsor due to operational challenges stemming from the coronavirus disease 2019 (COVID-19) pandemic, treatment limitations, rarity of the disease, and drug supply considerations.” (88% match in meaning)
• Study of Aztreonam for Inhalation in Children With Cystic Fibrosis and New Infection of the Airways by Pseudomonas Aeruginosa Bacteria
  “Study was terminated early by sponsor due to the challenges and risks introduced by Coronavirus disease 2019 (COVID-19) pandemic.” (87% match in meaning)
• Study to Evaluate the Efficacy and Safety of FX006 in Patients With Glenohumeral Osteoarthritis or Shoulder Adhesive Capsulitis
  “The study was terminated prematurely due to the COVID-19 pandemic creating uncertainty impacting trial progress and costs.” (84% match in meaning)
• Acceptability, Feasibility and Safety of a Yoga Program for Chronic Pain in Sickle Cell Disease
  “Study terminated due to COVID-19 pandemic.” (84% match in meaning)
• Optune Device - TT Field Plus Nivolumab and Ipilimumab for Melanoma With Brain Metastasis
  “The study was terminated early on 03/09/2022 due to low accrual during the COVID-19 pandemic.” (80% match in meaning)

Look deeper

• The official registry record (the source of truth)
• Record history: every change the sponsor made
• Open it in the database

Everything here comes from the current ClinicalTrials.gov record. The timeline uses the record’s dates; dates marked planned are the sponsor’s plans. The cause of death is an automatic, unverified label. This is research information, not medical advice.