Autopsy report · NCT03903640

Optune Device - TT Field Plus Nivolumab and Ipilimumab for Melanoma With Brain Metastasis

“The study was terminated early on 03/09/2022 due to low accrual during the COVID-19 pandemic.”

The sponsor’s own words in the registry.

Life of this trial

• Registered 6 months before it started.
• Ran for about 2 years 1 month before it stopped.
• 2 participants enrolled.
• Results were posted on the registry 6 months after it ended.

Vital statistics

Status

Terminated

Phase

Phase 2

Sponsor

Washington University School of Medicine

Sponsor type

University, hospital or other

Conditions

Melanoma With Brain Metastasis

Interventions

Optune; Nivolumab; Ipilimumab

Participants

2

Sites

1

Countries

United States

Trials that died the same way

• Acceptability, Feasibility and Safety of a Yoga Program for Chronic Pain in Sickle Cell Disease
  “Study terminated due to COVID-19 pandemic.” (85% match in meaning)
• Effects of Community-center Based Dietary Intervention on Frailty Prevention and Regression in the Elderly.
  “Due to the impacts of COVID-19, the study had to terminate.” (83% match in meaning)
• Stevia Extract and Glucose Homeostasis
  “The study has been terminated due to the pandemic.” (83% match in meaning)
• Orthodontic Approaches to Correct Deep Bite in Mixed Dentition Patients
  “The study was terminated due to difficulties in the recruitment attributed to the Covid19 pandemic.” (81% match in meaning)
• A Phase I Clinical Study for Evaluating the Safety and Efficacy of MASCT-I in Patients With Advanced Solid Tumors
  “The study was terminated early due to the COVID-19 pandemic and sponsor's funding constraints, based on promising preliminary safety and efficacy data.” (80% match in meaning)

Look deeper

• The official registry record (the source of truth)
• Record history: every change the sponsor made
• Open it in the database

Everything here comes from the current ClinicalTrials.gov record. The timeline uses the record’s dates; dates marked planned are the sponsor’s plans. The cause of death is an automatic, unverified label. This is research information, not medical advice.