Autopsy report · NCT04961801

Acalabrutinib for GVHD Prophylaxis in Allogeneic Hematopoietic Stem Cell Transplantation in Lymphomas and Leukemia

“Manufacturer AstraZeneca withdrew the study due to lack of funding”

The sponsor’s own words in the registry.

Life of this trial

• Withdrawn before it enrolled anyone. Its dates are the sponsor's plans, not events that happened.

Vital statistics

Status

Withdrawn

Phase

Phase 1, Phase 2

Sponsor

Shin Mineishi

Sponsor type

University, hospital or other

Conditions

Lymphoma; Leukemia

Interventions

Acalabrutinib, tacrolimus, methotrexate

Participants

0

Trials that died the same way

• MEDI4736 (Durvalumab) in Patients With Brain Metastasis From Epithelial-derived Tumors
  “Low accrual, funding withdrawn by AstraZeneca, and change in clinical practice” (77% match in meaning)
• Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of MEK162 in Noonan Syndrome Hypertrophic Cardiomyopathy
  “Study was withdrawn due to scientific and business considerations.” (68% match in meaning)
• Safety and Tolerability Study of AZD4831 in Patients With Heart Failure.
  “A decision was made to stop the study early when AstraZeneca evaluated the available data and it was considered that completing the study would provide limited additional information and unlikely to change the study conclusions.” (68% match in meaning)
• Characteristic Analysis and Surgical Exploration for Acetabular Roof Fractures: Multicenter Retrospective Cohort Study
  “Due to limited funding, the study is now being withdrawn.” (68% match in meaning)
• Immunotherapy After Transplantation for Skin Cancer Prevention in Organ Transplant Recipients
  “The study was withdrawn due to lack of financial support.” (67% match in meaning)

Look deeper

• The official registry record (the source of truth)
• Record history: every change the sponsor made
• Open it in the database

Everything here comes from the current ClinicalTrials.gov record. The timeline uses the record’s dates; dates marked planned are the sponsor’s plans. The cause of death is an automatic, unverified label. This is research information, not medical advice.