Autopsy report · NCT03756285

Safety and Tolerability Study of AZD4831 in Patients With Heart Failure.

“A decision was made to stop the study early when AstraZeneca evaluated the available data and it was considered that completing the study would provide limited additional information and unlikely to change the study conclusions.”

The sponsor’s own words in the registry.

Life of this trial

• Ran for about 1 year 5 months before it stopped.
• 41 participants enrolled.
• Results were posted on the registry 1 year 2 months after it ended.

Vital statistics

Status

Terminated

Phase

Phase 2

Sponsor

AstraZeneca

Sponsor type

Industry

Conditions

Heart Failure

Interventions

AZD4831; Placebo

Participants

41

Sites

13

Countries

Denmark, Finland, Netherlands, Sweden, United States

Trials that died the same way

• Acalabrutinib for GVHD Prophylaxis in Allogeneic Hematopoietic Stem Cell Transplantation in Lymphomas and Leukemia
  “Manufacturer AstraZeneca withdrew the study due to lack of funding” (68% match in meaning)
• Magnetic Resonance-guided High-Intensity Focused Ultrasound (MR-HIFU) Used for Mild Hyperthermia
  “Decision was made to not go forward with the study” (66% match in meaning)
• NIRS as a Continuous Noninvasive Monitoring System of Liver/Kidney Graft Perfusion
  “due to a decision by the research team not to continuos the study” (62% match in meaning)
• A Trial to Evaluate the Efficacy and Safety of PQ912 in Patients With Early AD
  “It has been made the strategic decision to terminate the study. This decision to terminate the study early is not being made for safety reasons.” (62% match in meaning)
• To Compare the Efficacy of I.V 200 mg Iron Sucrose and 500 mg Iron Sucrose to Treat Anemia in Pregnancy
  “The investigators decided not to proceed with this study” (61% match in meaning)

Look deeper

• The official registry record (the source of truth)
• Record history: every change the sponsor made
• Open it in the database

Everything here comes from the current ClinicalTrials.gov record. The timeline uses the record’s dates; dates marked planned are the sponsor’s plans. The cause of death is an automatic, unverified label. This is research information, not medical advice.