Lymphoma
Why trials studying Lymphoma stopped, in this sample of ClinicalTrials.gov.
49 stopped trials with a clear reason; 82% ended for non-scientific reasons.
| Reason | Trials | Share |
|---|---|---|
| slow accrual | 24 | 49% |
| funding business | 8 | 16% |
| logistics pi | 6 | 12% |
| safety | 4 | 8% |
| futility | 3 | 6% |
| regulatory | 2 | 4% |
| other | 2 | 4% |
Trials
- Immune Reconstitution Monitoring and Pneumococcal Vaccination in Patients Treated With CAR-T Cells
NCT07071909 · WITHDRAWN · funding business
“Funding unavailable” - DOLPHIN-VIVO: Diagnosis Of LymPHoma IN Vivo (In Vivo Phase)
NCT05010369 · TERMINATED · funding business
“Funding extension not granted” - ImmunoCARE: Rapid, Accurate COVID Testing to Reduce Hospitalization of Immunocompromised Individuals
NCT05655546 · TERMINATED · regulatory
“On May 13, 2024, the FDA released a communication that Cue Health tests should no longer be used.” - Xisomab 3G3 for the Prevention of Catheter-Associated Thrombosis in Patients With Cancer Receiving Chemotherapy
NCT04465760 · TERMINATED · slow accrual
“Insufficient accrual rate” - A Dose Finding and Safety Study of CC-220, Alone and in Combination With an Anti-CD20 Monoclonal Antibody (mAb) in Subjects With Relapsed or Refractory Lymphomas
NCT04464798 · TERMINATED · funding business
“Business objectives have changed.” - Autophagy Activation for the Alleviation of Cardiomyopathy Symptoms After Anthracycline Treatment, ATACAR Trial
NCT04190433 · WITHDRAWN · slow accrual
“Administratively closed due to low/no accrual” - Inotuzumab Ozogamicin and Chemotherapy in Treating Patients With Leukemia or Lymphoma Undergoing Stem Cell Transplantation
NCT03856216 · TERMINATED · slow accrual
“\<75% participation” - Long-term, Non-interventional, Observational Study Following Treatment With Fate Therapeutics FT500 Cellular Immunotherapy
NCT04106167 · TERMINATED · funding business
“This study was terminated by the Sponsor.” - Cancer Adverse Effects PReventIon With Care & Exercise: the CAPRICE Study
NCT03850171 · TERMINATED · logistics pi
“Due to the lack of financial and human resources the investigators were unable to continue the study. The targeted sample size was not achieved due to recruitment difficulties (mainly related to the Covid-19 pandemic).” - HeartPhone Cancer Survivors Trial 2019
NCT03953326 · TERMINATED · futility
“Futility in recruitment” - Ivabradine in the Management of Cardiac Autonomic Dysfunction Associated With Thoracic Radiation Therapy.
NCT03137537 · TERMINATED · funding business
“Funding terminated” - Reduced Intensity Conditioning Allogeneic Hematopoietic Stem Cell Transplant (HSCT) For Lymphoma
NCT02724904 · WITHDRAWN · logistics pi
“Drug logistics” - A Phase 1-2 Dose-Escalation and Cohort-Expansion Study of Oral Tomivosertib (eFT-508) in Subjects With Hematological Malignancies
NCT02937675 · TERMINATED · slow accrual
“patient recruitment” - Study of Genistein in Pediatric Oncology Patients (UVA-Gen001)
NCT02624388 · TERMINATED · slow accrual
“Poor enrollment” - A Study of Toca 511, a Retroviral Replicating Vector, Combined With Toca FC in Patients With Solid Tumors or Lymphoma (Toca 6)
NCT02576665 · TERMINATED · funding business
“Sponsor decision” - PET Imaging of Subjects Using 124I-PU-AD
NCT03371420 · TERMINATED · funding business
“Company has ceased operations” - Medical Treatment Decision Making Using Adaptive Conjoint Analysis
NCT02608307 · TERMINATED · slow accrual
“Slow accrual and COVID-19 restrictions” - Study of Loratadine for Pegfilgrastim Induced Bone Pain in Patients With Aggressive Lymphoma
NCT02392039 · TERMINATED · slow accrual
“Slow Accrual” - Development of a Biomarker Directed Strategy to Ameliorate Common Toxicities From Conventional Chemotherapy
NCT01921998 · SUSPENDED · logistics pi
“Trial has been suspended due to lack of resource and staff” - Chemotherapy Based on PET Scan in Treating Patients With Stage I or Stage II Hodgkin Lymphoma
NCT01390584 · TERMINATED · slow accrual
“slow accrual” - Presence of Donor-Derived DNA in Semen Samples From Cancer Survivors Who Underwent Donor Stem Cell Transplant
NCT01077440 · TERMINATED · logistics pi
“PI leaving institution” - RFT5-dgA Immunotoxin in Treating Patients With Relapsed or Refractory Cutaneous T-Cell Non-Hodgkin Lymphoma
NCT00667017 · TERMINATED · slow accrual
“Slow accrual.” - Pilot Study of MGd + High-dose MTX-Based Chemoimmunotherapy + RT for Newly Dx PCNSL
NCT00734773 · WITHDRAWN · funding business
“Lack of funding” - Intratumoral Dendritic Cell Vaccination Combined With Local Radiotherapy in Patients With Recurrent Lymphoma.
NCT00637117 · WITHDRAWN · logistics pi
“The study never opened and not sure if it ever will.” - Everolimus in Treating Older Patients With Mantle Cell Lymphoma Previously Treated With First-Line or Second-Line Chemotherapy
NCT00727207 · TERMINATED · slow accrual
“Lack of participations (8 of 25)” - Vaccine Therapy and GM-CSF in Treating Patients With CNS Lymphoma
NCT00621036 · WITHDRAWN · futility
“MyVax did not meet its primary endpoints” - Phase I/II Trial of VELCADE Plus Zevalin in Patients With Relapsed or Refractory Follicular Lymphoma
NCT00372905 · TERMINATED · slow accrual
“Study was closed permanently before the accrual goal was met due to slow accrual” - Genes in Predicting Outcome of Patients With DLBCL Treated With Rituximab and Combination Chemotherapy (R-CHOP)
NCT00450385 · TERMINATED · slow accrual
“Investigator Decision due to insufficient accrual.” - Study of Parathyroid Hormone Following Sequential Cord Blood Transplantation From an Unrelated Donor
NCT00393380 · TERMINATED · safety
“Study stopped because of toxicity concerns.” - Umbilical Cord Blood (UCB) Transplant, Fludarabine, Melphalan, and Anti-thymocyte Globulin (ATG) in Treating Patients With Hematologic Cancer
NCT00827099 · TERMINATED · safety
“Unacceptable morbidity \& mortality” - T-cell and B-cell Depletion in Allogeneic Peripheral Blood Stem Cell Transplantation
NCT00306332 · TERMINATED · other
“Interim analysis has shown that the objectives of this study can not be reached” - Treatment of Single or Double Umbilical Cord Trans + Graft-versus-host Disease (GVHD) Prophylaxis w/ Tacrolimus & Mycophenolate Mofetil
NCT00608517 · TERMINATED · slow accrual
“slow accrual” - Prednisolone or Dexamethasone Combined With Chemotherapy in Treating Young Patients With Newly Diagnosed Lymphoblastic Lymphoma
NCT00275106 · TERMINATED · safety
“Withdrawn due to an excess of toxic deaths” - G-CSF-Treated Donor Bone Marrow Transplant in Treating Patients With Hematologic Disorders
NCT00253552 · TERMINATED · logistics pi
“Terminated at request of PI as study was outdated.” - Effect of Tight Control of Blood Glucose During Hyper-CVAD Chemotherapy For Acute Lymphocytic Leukemia (ALL)
NCT00500240 · TERMINATED · futility
“Terminated early due to futility.” - Donor Stem Cell Transplant With No or Low-Intensity Chemotherapy Using Sirolimus and Treated Immune Cells to Treat Blood and Lymph Cancers
NCT00074490 · TERMINATED · slow accrual
“Premature closure due to inability to accrue to ARM IVD, cohorts 1 and 2” - Fludarabine, Cyclophosphamide, and Total-Body Irradiation Followed by Cyclosporine and Mycophenolate Mofetil in Treating Patients Who Are Undergoing a Donor Umbilical Cord Blood Transplant for Hematologic Cancer
NCT00255684 · TERMINATED · slow accrual
“low accrual” - CpG 7909 in Treating Patients Who Have Undergone Autologous Stem Cell Transplant
NCT00369291 · TERMINATED · slow accrual
“Slow accrual” - Autologous and Allogenic Transplantation With Campath-1H for T-Cell Lymphoma
NCT00505921 · TERMINATED · slow accrual
“Slow Accrual.” - Treating Patients With Recurrent PCNSL With Carboplatin/BBBD and Adding Rituxan To The Treatment Regimen
NCT00074165 · TERMINATED · slow accrual
“Lack of accrual” - Moxifloxacin Compared With Ciprofloxacin/Amoxicillin in Treating Fever and Neutropenia in Patients With Cancer
NCT00062231 · TERMINATED · slow accrual
“low accrual” - Busulfan and Fludarabine Before Donor Stem Cell Transplant in Treating Patients With Hematologic Cancer
NCT00301912 · WITHDRAWN · slow accrual
“Withdrawn because study never opened to accrual” - Antibody Therapy in Treating Patients With Refractory or Relapsed Non-Hodgkin's Lymphoma or Chronic Lymphocytic Leukemia
NCT00014560 · TERMINATED · safety
“Medarex (supplier of BsAb) stopped study due to toxicities experienced at other sites on unrelated trials halting manufacturing of BsAb” - Peripheral Stem Cell Transplantation to Prevent Neutropenia in Patients Receiving Chemotherapy for Relapsed or Refractory Non-Hodgkin's Lymphoma
NCT00005787 · TERMINATED · slow accrual
“Per PI due to poor/inadequate accrual.” - 12-O-Tetradecanoylphorbol-13-acetate in Treating Patients With Hematologic Cancer or Bone Marrow Disorder
NCT00004058 · TERMINATED · other
“At this time it is felt that we will not gain further information from an additional patients.” - Monoclonal Antibody Therapy in Treating Patients With Non-Hodgkin's Lymphoma
NCT00004874 · TERMINATED · regulatory
“lack of FDA approval” - Temozolomide in Treating Patients With Mycosis Fungoides or Sezary Syndrome
NCT00004106 · TERMINATED · slow accrual
“Per Data Monitoring Committee given the poor/inadequate accrual.” - Chemotherapy Plus Interferon Alfa Alone or With Radiation Therapy and Peripheral Stem Cell Transplantation in Treating Patients With Stage III or Stage IV Follicular Non-Hodgkin's Lymphoma
NCT00003152 · TERMINATED · slow accrual
“low accrual” - Bortezomib and Rituximab in Treating Patients With Relapsed or Refractory B-Cell Non-Hodgkin's Lymphoma
NCT00265928 · TERMINATED · slow accrual
“Withdrawn for poor accrual”
Reasons are labeled automatically and are unverified. See the methodology. This is research information, not medical advice. Search the full database.