Autopsy report · NCT04264533

Vitamin C Infusion for the Treatment of Severe 2019-nCoV Infected Pneumonia

“the study was started in the second half of the outbreak, and the number of qualifying COVID-19 patients decreased with the control of the epidemic so that we had to stop our trial before reaching the predefined sample size.”

The sponsor’s own words in the registry.

Life of this trial

• Ran for about 1 month before it stopped.
• 56 participants enrolled.
• No results are posted on the registry.

Vital statistics

Status

Terminated

Phase

Phase 2

Sponsor

ZhiYong Peng

Sponsor type

University, hospital or other

Conditions

Vitamin C; Pneumonia, Viral; Pneumonia, Ventilator-Associated

Interventions

VC; Sterile Water for Injection

Participants

56

Sites

1

Countries

China

Trials that died the same way

• Metformin's Effect on Drug Metabolism in Patients With Type 2 Diabetes
  “Slow recruitment due to COVID-19, the study was stopped when recruited numbers fulfilled the pre-defined lower sample size.” (74% match in meaning)
• Improving 24-hour Blood Pressure in Obstructive Sleep Apnea
  “Covid-19 Pandemic prevented this study from beginning” (72% match in meaning)
• Pedicle Osteotomy for Stenosis Trial
  “In light of the ongoing COVID-19 pandemic and its impact on clinical trials” (71% match in meaning)
• Study Assessing Vagus Nerve Stimulation in CoViD-19 Respiratory Symptoms
  “A total of 21 patients were enrolled in the study resulting in 97 total collected specimen time points. Patient recruitment was halted due to greatly decreased numbers of patient hospitalizations for Covid-19.” (71% match in meaning)
• Riociguat in Patients With Operable CTEPH Prior to Pulmonary Endarterectomy (PEA Bridging Study)
  “The study was stopped due to slower than expected recruitment and the additional limitations on clinical research imposed by the COVID-19 pandemic, both of which made study completion within a reasonable timeframe appear unlikely.” (69% match in meaning)

Look deeper

• The official registry record (the source of truth)
• Record history: every change the sponsor made
• Open it in the database

Everything here comes from the current ClinicalTrials.gov record. The timeline uses the record’s dates; dates marked planned are the sponsor’s plans. The cause of death is an automatic, unverified label. This is research information, not medical advice.