Autopsy report · NCT04382391

Study Assessing Vagus Nerve Stimulation in CoViD-19 Respiratory Symptoms

“A total of 21 patients were enrolled in the study resulting in 97 total collected specimen time points. Patient recruitment was halted due to greatly decreased numbers of patient hospitalizations for Covid-19.”

The sponsor’s own words in the registry.

Life of this trial

• Registered 1 month before it started.
• Ran for about 2 years 11 months before it stopped.
• 21 participants enrolled.
• Results were posted on the registry 1 year 1 month after it ended.

Vital statistics

Status

Terminated

Phase

Na

Sponsor

Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)

Sponsor type

University, hospital or other

Conditions

COVID; Corona Virus Infection; Respiratory Failure; Respiratory Distress Syndrome, Adult; ARDS, Human; SARS (Severe Acute Respiratory Syndrome)

Interventions

gammaCore® Sapphire (non-invasive vagus nerve stimulator); Standard of care therapies

Participants

21

Sites

2

Countries

United States

Trials that died the same way

• Safety and Efficacy of Vibro-tactile Feedback for Patients Who Underwent Lower Limb Amputation
  “recruitment rate of patients was not sufficient during COVID-19; problems with the quality of the primary outcome data collected” (81% match in meaning)
• A Study of Orally Administered JBPOS0101 in Refractory Infantile Spasms Patients
  “Difficulty with patient recruitment due to COVID-19” (79% match in meaning)
• Iron Isomaltoside Compared With Iron Sucrosein Peritoneal Dialysis Patients
  “Difficult patient recruitment due to COVID-19 epidemic” (78% match in meaning)
• Ultrasonography in Norwegian Emergency Department Patients With Suspected Covid-19 Infection
  “lack of Covid-19 patients” (75% match in meaning)
• Piloting Conversation Cards for Adolescents
  “Ongoing COVID-19 restrictions and very low (in-person) clinical activity prevented participant recruitment.” (75% match in meaning)

Look deeper

• The official registry record (the source of truth)
• Record history: every change the sponsor made
• Open it in the database

Everything here comes from the current ClinicalTrials.gov record. The timeline uses the record’s dates; dates marked planned are the sponsor’s plans. The cause of death is an automatic, unverified label. This is research information, not medical advice.