Autopsy report · NCT00085761

Study of NGX-4010 for Treatment of Painful HIV-Associated Neuropathy

“Terminated in view of the C107 findings demonstrating efficacy at doses of 90 and 30 minutes”

The sponsor’s own words in the registry.

Life of this trial

• No results are posted on the registry.

Vital statistics

Status

Terminated

Phase

Phase 3

Sponsor

NeurogesX

Sponsor type

Industry

Conditions

HIV Infections; Peripheral Nervous System Diseases; Pain

Interventions

Capsaicin Dermal Patch

Sites

2

Countries

United States

Trials that died the same way

• Safety and Efficacy Evaluation of Bosutinib Plus Atezolizumab in Newly Diagnosed Chronic Leukemia Adult Patients
  “The study has been prematurely terminated due to the onset of 2 dose limiting toxicities in 2 patients.” (65% match in meaning)
• Dose-Range Finding Study for MK0893 (0893-008)
  “Sufficient data regarding the dose-response to MK-0893 had been obtained from the first cohort of the study to assess the safety and efficacy” (60% match in meaning)
• A Study Of Safety, Tolerability And Effectiveness Of Recifercept In Children With Achondroplasia
  “The study was terminated due to lack of efficacy at any of the tested doses on 18th November 2022. The decision to terminate the study is not related to a safety concern.” (58% match in meaning)
• A Dose Escalation Trial of PR610 Treating Patients With Solid Tumors
  “Study was prematurely discontinued due to unacceptable toxicity.” (56% match in meaning)
• Irreversible Electroporation + Nivolumab for Patients With Metastatic Pancreatic Cancer
  “The study was terminated on the basis on an evaluation of the safety and efficacy of the 9 included patients of which 2 of the patients were excluded before receiving any study treatments, thus 7 patients were treated in the study.” (56% match in meaning)

Look deeper

• The official registry record (the source of truth)
• Record history: every change the sponsor made
• Open it in the database

Everything here comes from the current ClinicalTrials.gov record. The timeline uses the record’s dates; dates marked planned are the sponsor’s plans. The cause of death is an automatic, unverified label. This is research information, not medical advice.