Autopsy report · NCT05730556

A Study of Remote Electrical Neuromodulation for Acute Procedural Pain

“Enough data was collected to demonstrate device efficacy at interim analysis”

The sponsor’s own words in the registry.

Life of this trial

• Ran for about 1 year 7 months before it stopped.
• 80 participants enrolled.
• Results were posted on the registry 1 year 2 months after it ended.

Vital statistics

Status

Terminated

Phase

Na

Sponsor

Mayo Clinic

Sponsor type

University, hospital or other

Conditions

Chronic Migraine

Interventions

Nerivio ®; Sham

Participants

80

Sites

1

Countries

United States

Trials that died the same way

• A Study to Assess the Anti-fatigability Effect of CK-2127107 in Elderly Male and Female Subjects With Limitations in Mobility
  “Lack of efficacy determined at interim analysis” (66% match in meaning)
• Evaluation of Directional Recording and Stimulation Using spiderSTN
  “This study was structured in 2 phases, and was stopped after the first phase. The collected data will be used to improve the device and prepare future studies.” (66% match in meaning)
• Evaluation of Performance and Safety of Carbopol 980 NF 0.2%- Based Medical Device in the Management of Patients With Glaucomar or Ocular Hypertension and Concomitant Dry Eye Syndrome on Multiple Long-term Topical Hypotensive Therapy
  “The investigation was prematurely interrupted with 65 patients enrolled due to difficulties in recruiting patients. However the results observed in the interim analysis demonstrate the performance of the investigational device.” (64% match in meaning)
• LBH589 in Refractory Myelodysplastic Syndromes (MDS)
  “Per protocol, the results of a planned interim analysis demonstrated insufficient efficacy and led to early termination of the study.” (62% match in meaning)
• An in Vivo Comparison of the Debridement Efficiency of Needle Irrigation Versus Ultrasonic Irrigation
  “Manufacturer changed device so no study will be done; ie it was never started” (60% match in meaning)

Look deeper

• The official registry record (the source of truth)
• Record history: every change the sponsor made
• Open it in the database

Everything here comes from the current ClinicalTrials.gov record. The timeline uses the record’s dates; dates marked planned are the sponsor’s plans. The cause of death is an automatic, unverified label. This is research information, not medical advice.