Mayo Clinic

Why trials sponsored by Mayo Clinic stopped, in this sample of ClinicalTrials.gov.

86 stopped trials with a clear reason; 91% ended for non-scientific reasons.

Trials

• Allogenic Adipose-derived Mesenchymal Stem Cells(AMSCs) for Epilepsy During Deep Brain Stimulation(DBS) Surgery
  NCT06280092 · TERMINATED · logistics pi
  “PI has passed away”
• Ibrutinib for the Prevention of Chronic Graft-Versus-Host Disease in Patients Undergoing Donor Stem Cell Transplant
  NCT06271616 · TERMINATED · slow accrual
  “poor accrual”
• Defining Musical Toxicity and Its Effect on Patient Well-being
  NCT06494046 · WITHDRAWN · logistics pi
  “Resident working with study left institution”
• Health Care Provider Preventiomter Study
  NCT05387590 · WITHDRAWN · logistics pi
  “Unable to conduct study due to equipment not operational from study Sponsor team in Germany”
• Relationship Between Alterations in the GI Microbiome and GI Inflammation on Symptom Burden in Women With Breast Cancer Receiving Chemotherapy
  NCT06238986 · TERMINATED · funding business
  “Lack of funding”
• Treatment of Sinus Headache Using a Novel Device That Combines Acoustic Vibration With Oscillating Expiratory Pressure
  NCT05479604 · TERMINATED · regulatory
  “participant non-compliance”
• Focused Shock Wave Therapy Outcomes in Peyronie's Disease and Erectile Dysfunction
  NCT05646602 · WITHDRAWN · slow accrual
  “No participants enrolled”
• Xperience™ vs Normal Saline Irrigation Solution for Decreasing Bioburden After Primary Total Hip and Knee Arthroplasty
  NCT05577936 · WITHDRAWN · funding business
  “Delay in funding.”
• ALgorithms Adapted From Remote Monitoring
  NCT05782140 · TERMINATED · slow accrual
  “Low enrollment, completion of funding”
• A Pneumatic Compression Device for the Treatment of Lymphedema in Patients With Stage II-IV Head and Neck Cancer After Chemoradiation
  NCT05512767 · WITHDRAWN · logistics pi
  “PI retired and study not moving forward”
• Evaluating the Accuracy of Microvessel Ultrasound Imaging for Detecting Extent of Disease in Patients With Angiosarcoma of the Skin
  NCT05729425 · TERMINATED · slow accrual
  “Unable to recruit participants due to rare disease”
• COVID-FIS: Pilot in COVID-19 (SARS-CoV-2) of Fisetin in Older Adults in Nursing Homes
  NCT04537299 · TERMINATED · futility
  “The DSMB and NIA determined the study should be stopped due to futility.”
• Evaluation of 18F-TFB PET/CT Scan in Patients With Differentiated Thyroid Cancer
  NCT05575440 · TERMINATED · slow accrual
  “Slow accrual; lack of eligible study participants”
• Adaptive Virtual Consultation Tool to Enhance Education and Understanding in Patients with Prostate Cancer
  NCT06016504 · TERMINATED · slow accrual
  “Low/slow accrual”
• Catheter Ablation of Ventricular Arrhythmia Reduces Skin Sympathetic Activity
  NCT04837183 · TERMINATED · other
  “This study was closed before its planned primary completion date because early data indicated that VT ablation had little impact on sympathetic nerve activity in short-term follow up.”
• Novel Antiaging Regenerative Skin Care Regimen Containing Human Platelet Extract (HPE)
  NCT05457491 · TERMINATED · logistics pi
  “Principal Investigator discretion”
• A Study to Evaluate the Safety and Tolerability of Virtual Reality to Treat Gastroparesis
  NCT05079568 · SUSPENDED · funding business
  “Pending funding”
• FEIBA to Optimize Postcardiopulmonary Bypass Hemostasis in Pediatric Cardiac Patients
  NCT05020483 · WITHDRAWN · slow accrual
  “Patient population changed and no subjects eligible for the study.”
• Study of Intravenous Erenumab in Patients With Status Migrainosus
  NCT04920331 · WITHDRAWN · slow accrual
  “No Participants Enrolled”
• Promoting Equity for Cancer Screening and Follow-up
  NCT04831827 · WITHDRAWN · logistics pi
  “Insufficient study resources and change in practice.”
• Non-invasive Near-infrared Spectroscopy (NIRS) Versus Invasive Licox Intracranial Pressure
  NCT04247321 · WITHDRAWN · other
  “• Withdrawn: Study halted prematurely, prior to enrollment of first participant”
• Oral Tamoxifen vs. TamGel vs. Control in Women With Atypical Hyperplasia, Lobular Carcinoma In Situ, or Increased Breast Cancer Risk
  NCT04570956 · TERMINATED · funding business
  “grant and funding expired”
• Continuous Data Collection and Analysis for Stroke Prevention Using a Wearable Sensor
  NCT03441022 · WITHDRAWN · logistics pi
  “Unable to obtain equipment from Sponsor to be able to proceed with the study.”
• Manipulating and Optimizing Brain Rhythms for Enhancement of Sleep
  NCT05089682 · TERMINATED · logistics pi
  “Unable to enroll subjects due to COVID and complexity of study.”
• The Role of the Pharmacist and Pharmacogenomics in the Care of Seriously Ill Patients
  NCT04251520 · TERMINATED · slow accrual
  “Unable to recruit participants”
• Adipose Derived SVF for Aero-digestive & Enterocutaneous Fistulae
  NCT03792360 · WITHDRAWN · slow accrual
  “Study closed due to lack of patient enrollment.”
• A Study to Evaluate Rapid Throughput Screening for Human COVID-19 Infection
  NCT04725097 · TERMINATED · other
  “Interim analysis indicated adaptions may be required.”
• Docetaxel With or Without Bintrafusp Alfa for the Treatment of Advanced Non-small Cell Lung Cancer
  NCT04396535 · TERMINATED · futility
  “EMD Serono recommendation based on three other studies that failed to show benefit for bintrafusp alfa”
• Autophagy Activation for the Alleviation of Cardiomyopathy Symptoms After Anthracycline Treatment, ATACAR Trial
  NCT04190433 · WITHDRAWN · slow accrual
  “Administratively closed due to low/no accrual”
• RBX7455 Before Surgery for the Treatment of Operable Breast Cancer
  NCT04139993 · TERMINATED · slow accrual
  “poor accrual”
• A Study to Implement and Evaluate REFLECT Communication Curriculum for Oncology Based Medical Graduate Students
  NCT04557696 · TERMINATED · slow accrual
  “Resident/fellow feedback indicated study factors made it difficult to participate and busy schedules did not accommodate to consent.”
• Feasibility in the Prophylaxis of Radiation Dermatitis Severity
  NCT04715386 · TERMINATED · slow accrual
  “slow accrual; investigator retired”
• Impact of Near-Infrared Vein Mapping on Outcomes and Satisfaction After Botox/Filler Treatment
  NCT04240080 · WITHDRAWN · slow accrual
  “Practice volume was low and resulted in a lack of participant accrual”
• High Versus Low Bicarbonate Bath in Critically-ill Patients Receiving Continuous Renal Replacement Therapy
  NCT03846258 · WITHDRAWN · slow accrual
  “Due to the fact that we were unable to find subjects who met all inclusion and exclusion criteria it was determined to withdraw this study.”
• Intraoperative Brain Microdialysis to Assess Neuroinflammation in Epileptic Tissue Immediately Prior to Surgical Resection.
  NCT04531722 · WITHDRAWN · funding business
  “No subjects were enrolled and there was not funding to continue the study”
• The Role of Bathing Additives in the Treatment of Pediatric Atopic Dermatitis
  NCT03775590 · TERMINATED · slow accrual
  “Study closed due to lack of enrollment.”
• Low Cost QTc Meter for Long QT Syndrome Screening in Primary Care
  NCT04441892 · TERMINATED · logistics pi
  “COVID, lack of funding and interruption of patient recruitment led to ending the study early.”
• A Comparison of Incisionless Ultrasound Guided Thread Carpal Tunnel Release and Mini Open Carpal in Patients With Bilateral Carpal Tunnel Syndrome
  NCT03906604 · TERMINATED · slow accrual
  “Difficulty recruiting for open carpal tunnel study arm”
• Radiofrequency Ablation for Amiodarone-induced Thyrotoxicosis
  NCT03720210 · TERMINATED · slow accrual
  “Very low enrollment”
• Institutional Outcome Data From Per-oral Plication of the Esophagus
  NCT03875365 · TERMINATED · logistics pi
  “PI left the institution before enrollment was complete.”
• Direct Tumor Microinjection and FDG-PET in Testing Drug Sensitivity in Patients With Relapsed or Refractory Non-Hodgkin Lymphoma, Hodgkin Lymphoma, or Stage IV Breast Cancer
  NCT03432741 · TERMINATED · funding business
  “funding - sponsor filing Chapter 11 bankruptcy”
• Subcu Administration of CD-NP in Heart Failure Patients With Left Ventricular Assist Device Support
  NCT03091998 · WITHDRAWN · funding business
  “No funding available”
• Bicalutamide and Raloxifene Hydrochloride in Treating Patients With Prostate Cancer Undergoing Surgery
  NCT03147196 · WITHDRAWN · slow accrual
  “lack of accrual”
• Ultrasound Evaluation of Crohn's Disease
  NCT03235180 · TERMINATED · funding business
  “Unable to secure funding.”
• Nivolumab in Treating Patients With Relapsed or Refractory Peripheral T-cell Lymphoma
  NCT03075553 · TERMINATED · slow accrual
  “due to poor response”
• Ibrutinib, Lenalidomide, and Dexamethasone in Treating Patients With Multiple Myeloma Ineligible for Transplant
  NCT03015792 · TERMINATED · funding business
  “Drug company decided to not fund the phase 2 portion”
• Dermatome Electrical Stimulation on Individuals With Overweight and Class I Obesity
  NCT03261531 · TERMINATED · manufacturing supply
  “Device failure”
• SMOFLipid in Patients Who Are Intralipid Intolerant
  NCT03054948 · WITHDRAWN · other
  “Redesign of study protocol.”
• Automatic Periodic Stimulation and Continuous Electromyography (EMG) for Facial Nerve Monitoring During Parotidectomy
  NCT03172520 · TERMINATED · logistics pi
  “Limitations in timing and personnel”
• Human Mesenchymal Stem Cells in the Synovial Fluid of the Hip
  NCT02941666 · TERMINATED · logistics pi
  “Study staff was unable to collect proper samples to meet study goals”
• Addressing Post Cessation Weight Gain
  NCT02412631 · TERMINATED · manufacturing supply
  “Lorcaserin removed from market”
• Immune Predictors of Response to Pembrolizumab Therapy in Stage IV Melanoma Patients
  NCT02744209 · TERMINATED · slow accrual
  “Low accrual”
• Everolimus and Brentuximab Vedotin in Treating Patients With Relapsed or Refractory Hodgkin Lymphoma
  NCT02254239 · TERMINATED · funding business
  “funding withdrawal”
• Achalasia Patient Reported Outcomes
  NCT02606578 · TERMINATED · logistics pi
  “Study's original Principal Investigator no longer at the institution.”
• Patients With Patent Foramen Ovale and Endocardial Device Leads on Apixaban for Prevention of Paradoxical Emboli
  NCT02378623 · WITHDRAWN · funding business
  “Sponsor withdrew funding - May 2016”
• Iron Sucrose in Adolescents With Iron Deficiency and Postural Orthostatic Tachycardia Syndrome (POTS)
  NCT01978535 · TERMINATED · slow accrual
  “Difficulty in recruiting subjects.”
• PGC-1 & Muscle Mitochondrial Dysfunction in Diabetes
  NCT02282423 · TERMINATED · logistics pi
  “PI job change”
• The Affect of Low-Volume Bowel Preparation for Hospitalized Patients Colonoscopies
  NCT01978509 · TERMINATED · slow accrual
  “Lack of enrollment”
• Assessing the Efficacy of Steroid Treatment of Achalasia
  NCT01903486 · WITHDRAWN · slow accrual
  “Unable to recruit participants.”
• Oral Ketamine in the Treatment of Depression and Anxiety in Patients With Cancer
  NCT01680172 · TERMINATED · slow accrual
  “Slow enrollment”
• Polyphenon E in Treating Patients With High-Risk of Colorectal Cancer
  NCT01606124 · TERMINATED · manufacturing supply
  “pending expiration of the supply of study agent.”
• Chest Computed Tomography (CT) Screening Study With Antibody Testing
  NCT01203579 · WITHDRAWN · funding business
  “Due to lack of funding”
• Prospective Randomized Trial Comparing Robotic Versus Open Radical Prostatectomy
  NCT01365143 · TERMINATED · slow accrual
  “Closing due to slow enrollment”
• Megestrol Acetate in Treating Weight Loss or Anorexia in Young Patients With Malignancies Who Are Undergoing Radiation Therapy and/or Chemotherapy
  NCT01200602 · TERMINATED · slow accrual
  “The study closed due to slow accrual.”
• Lusedra (Fospropofol Disodium) for Minimal to Moderate Sedation for Regional Anesthesia Block Prior to Orthopedic Surgery
  NCT01195103 · TERMINATED · funding business
  “Funding terminated by funding source.”
• Lopinavir and Ritonavir in Improving Immune Response to Vaccines in Patients With Complete Remission Following A Bone Marrow Transplant for Hodgkin Lymphoma
  NCT01165645 · WITHDRAWN · slow accrual
  “no patients enrolled”
• Eculizumab to Prevent Antibody-mediated Rejection in ABO Blood Group Incompatible Living Donor Kidney Transplantation
  NCT01095887 · TERMINATED · slow accrual
  “Poor enrollment”
• Calcium and Magnesium in Preventing Peripheral Neuropathy Caused by Ixabepilone in Patients With Breast Cancer
  NCT00998738 · TERMINATED · slow accrual
  “lack of accrual”
• Study of Low Dose Nesiritide With or Without Sildenafil in Congestive Heart Failure Patients With Renal Dysfunction
  NCT00818701 · TERMINATED · other
  “started a NIH study that is competing for same subjects”
• Vaccine Therapy in Treating Patients With Non-Metastatic Prostate Cancer
  NCT00814892 · TERMINATED · funding business
  “Study was terminated due to funding issues.”
• Study Evaluating Benefit of Using Fibrin Glue in Septorhinoplasty
  NCT00713596 · TERMINATED · logistics pi
  “Lead investigator moved to a new medical center; study was stopped when he left.”
• Prolotherapy Versus Steroids for Thumb Carpo-metacarpal Joint Arthritis
  NCT00685880 · TERMINATED · slow accrual
  “Unable to recruit adequate numbers of patients”
• Anti-thymocyte Globulin and Melphalan in Treating Patients With Relapsed Multiple Myeloma
  NCT00635024 · TERMINATED · slow accrual
  “Due to competing trials, this study is permanenlty closed to patient acrrual.”
• Over Active Bladder Instillation Study - Botox
  NCT00667095 · TERMINATED · logistics pi
  “Study terminated early due to PI's extended medical leave.”
• Sorafenib and Letrozole, Anastrozole, or Exemestane in Treating Postmenopausal Women With Estrogen Receptor-Positive and/or Progesterone Receptor-Positive Metastatic Breast Cancer
  NCT00573755 · TERMINATED · slow accrual
  “lack of participant accrual”
• Renal Protective Effect of ACEI and ARB in Primary Hyperoxaluria
  NCT00280215 · WITHDRAWN · slow accrual
  “Inadequate number of patients, lack of funding”
• Comparison of Coronary CT With IVUS in Heart Transplant Population
  NCT00589524 · WITHDRAWN · slow accrual
  “Difficult recruitment -”
• Aspirin for Treatment of Multiple Sclerosis-Related Fatigue
  NCT00467584 · TERMINATED · futility
  “Interim analysis indicated treatment unlikely effective;slow recruitment”
• Cathartic-Free DECT Colonography for Detection of Colonic Polyps
  NCT00587028 · TERMINATED · funding business
  “Administrative closed due to funding”
• Prophylactic Pulmonary Vein Isolation Study
  NCT00587899 · TERMINATED · slow accrual
  “enrollment has been lower than anticipated due to growth in the minimally invasive mitral valve repair practice.”
• Islet Transplantation for Type 1 Diabetes Mellitus
  NCT00437398 · TERMINATED · slow accrual
  “The study was terminated early due to difficulty in recruiting subjects, and ran short of funds.”
• Electroacupuncture in Treating Chronic Dry Mouth Caused By Radiation Therapy in Patients With Head and Neck Cancer
  NCT00623129 · TERMINATED · slow accrual
  “Slow accrual; did not meet accrual goal”
• Near Infrared Light for the Treatment of Painful Peripheral Neuropathy
  NCT00125268 · TERMINATED · slow accrual
  “Unable to enroll enough patients”
• Nicotine in Treating "Hunger Pain" in Patients With Malignant Bowel Obstruction Caused By Cancer
  NCT00425906 · WITHDRAWN · slow accrual
  “No patient enrollment occurred.”
• Budesonide Versus Placebo for the Treatment of Lymphocytic Colitis
  NCT00217022 · TERMINATED · slow accrual
  “Study closed early, because of low enrollment.”
• BELIEVE Study: Nesiritide and Post Myocardial Infarction Left Ventricular Modeling
  NCT00252213 · TERMINATED · slow accrual
  “recruitment of subjects was halted prematurely. recruiting subjects halted prematurely”

Reasons are labeled automatically and are unverified. See the methodology. This is research information, not medical advice. Search the full database.