Autopsy report · NCT06190028

Evaluation of Performance and Safety of Carbopol 980 NF 0.2%- Based Medical Device in the Management of Patients With Glaucomar or Ocular Hypertension and Concomitant Dry Eye Syndrome on Multiple Long-term Topical Hypotensive Therapy

“The investigation was prematurely interrupted with 65 patients enrolled due to difficulties in recruiting patients. However the results observed in the interim analysis demonstrate the performance of the investigational device.”

The sponsor’s own words in the registry.

Life of this trial

• Registered 6 months after it had already started.
• Ran for about 1 year 9 months before it stopped.
• 65 participants enrolled.
• No results are posted on the registry.

Vital statistics

Status

Terminated

Phase

Na

Sponsor

Fidia Farmaceutici s.p.a.

Sponsor type

Industry

Conditions

Dry Eye Syndrome; Glaucoma and Concomitant Dry Eye Syndrome; Ocular Hypertension and Concomitant Dry Eye Syndrome; Multiple Long-term Topical Hypotensive Therapy

Interventions

Iridium A Gel

Participants

65

Sites

3

Countries

Italy

Trials that died the same way

• Optical Brain Pulse Monitor: Validation Of Cerebral Oximetry Monitoring (OBPM:VOCOM) Study.
  “The decision was made to withdraw this study prior to recruitment to make further changes to the investigational device.” (68% match in meaning)
• LBH589 in Refractory Myelodysplastic Syndromes (MDS)
  “Per protocol, the results of a planned interim analysis demonstrated insufficient efficacy and led to early termination of the study.” (68% match in meaning)
• Effectiveness of Periocular Drug Injection in CATaract Surgery
  “Results of interim analysis: stop the trial due to one group being significantly different from the other three groups. Furthermore, shortage of study medication.” (67% match in meaning)
• A 3 Years Naturalistic Cohort Survey of Altis Single Incision Sling System For Female Stress Urinary Incontinence
  “The minimum of enrolled subject defined in the protocol was 180 patients and it was greatly exceeded. Therefore the study was terminated by the sponsor to perform the study analysis.” (67% match in meaning)
• Prevention Trial: Immune-tolerance With Alum-GAD (Diamyd) and Vitamin D3 to Children With Multiple Islet Autoantibodies
  “The study was interrupted early and terminated when only 26 out of 80 patients were enrolled due to new clinical study results indicating that the current study would not be informative.” (66% match in meaning)

Look deeper

• The official registry record (the source of truth)
• Record history: every change the sponsor made
• Open it in the database

Everything here comes from the current ClinicalTrials.gov record. The timeline uses the record’s dates; dates marked planned are the sponsor’s plans. The cause of death is an automatic, unverified label. This is research information, not medical advice.