Autopsy report · NCT05651633

Analgesic Ear Drops for Children With Acute Otitis Media

“Trial accrual problems”

The sponsor’s own words in the registry.

Life of this trial

• Registered 1 year 1 month after it had already started.
• Ran for about 2 years 3 months before it stopped.
• 29 participants enrolled.
• Results were posted on the registry 2 years 6 months after it ended.

Vital statistics

Status

Terminated

Phase

Phase 3

Sponsor

UMC Utrecht

Sponsor type

University, hospital or other

Conditions

Acute Otitis Media; Pain

Interventions

lidocaine hydrochloride 5mg/g

Participants

29

Sites

1

Countries

Netherlands

Trials that died the same way

• Detection of Tumor DNA in Blood Samples From Patients With Early Stage Cancer and "Healthy Controls"
  “Accrual difficulties” (71% match in meaning)
• Loncastuximab Tesirine for the Treatment of Relapsed or Refractory B-Cell Malignancies
  “The trial closed early due to slow accrual.” (66% match in meaning)
• Copanlisib in Combination With T-DM1 in Pretreated Unresectable Locally Advanced or Metastatic HER2-positive Breast Cancer
  “Accrual rate to date was too low to finish the trial in a reasonable timeframe” (66% match in meaning)
• A Study of Contrast-Enhanced Mammography (CEM) Scans in People With Breast Cancer
  “Challenges to participant accrual” (65% match in meaning)
• PET/CT in Evaluating Response to Chemotherapy in Patients With Breast Cancer
  “Insufficient accrual” (62% match in meaning)

Look deeper

• The official registry record (the source of truth)
• Record history: every change the sponsor made
• Open it in the database

Everything here comes from the current ClinicalTrials.gov record. The timeline uses the record’s dates; dates marked planned are the sponsor’s plans. The cause of death is an automatic, unverified label. This is research information, not medical advice.