Autopsy report · NCT05525455

TT-816 As Monotherapy or in Combination with a PD-1 Inhibitor in Patients with Advanced Cancers (SEABEAM) (MK3475-E88)

“Company operational decision. Decision to stop study is not due to safety or efficacy concerns.”

The sponsor’s own words in the registry.

Life of this trial

• Ran for about 1 year before it stopped.
• 9 participants enrolled.
• No results are posted on the registry.

Vital statistics

Status

Terminated

Phase

Phase 1, Phase 2

Sponsor

Teon Therapeutics, Inc.

Sponsor type

Industry

Conditions

Advanced Cancer; Advanced Solid Tumor; Cancer; Oncology

Interventions

TT-816; A PD-1 inhibitor

Participants

9

Sites

5

Countries

United States

Trials that died the same way

• A Trial to Evaluate the Efficacy and Safety of PQ912 in Patients With Early AD
  “It has been made the strategic decision to terminate the study. This decision to terminate the study early is not being made for safety reasons.” (77% match in meaning)
• Efficacy, Safety, Tolerability and Pharmacokinetics of SUN13837 to Treat Acute Stroke
  “study was stopped for business/administrative reasons and not for patient safety concerns” (75% match in meaning)
• Patient-reported Outcomes in Subjects Treated With ReFacto AF Routine Prophylaxis
  “Company decision to not conduct study” (75% match in meaning)
• Effects of JNJ-53718678 in Adult and Adolescent Participants Who Had a Hematopoietic Stem Cell Transplantation and Who Are Infected With Respiratory Syncytial Virus (RSV)
  “A strategic decision was made to discontinue the study. The decision was not based on a safety concern.” (75% match in meaning)
• Study Evaluating the Efficacy and Safety of IPI 504 in Patients With Advanced Dedifferentiated Liposarcoma
  “Company decision not to start the study” (74% match in meaning)

Look deeper

• The official registry record (the source of truth)
• Record history: every change the sponsor made
• Open it in the database

Everything here comes from the current ClinicalTrials.gov record. The timeline uses the record’s dates; dates marked planned are the sponsor’s plans. The cause of death is an automatic, unverified label. This is research information, not medical advice.