Autopsy report · NCT04900428

Study to Evaluate a Single Intranasal Dose of STI-2099 (COVI-DROPS™) in Outpatient Adults With COVID-19 (UK)

“Study was terminated at interim analysis due to drops not working on new variants”

The sponsor’s own words in the registry.

Life of this trial

• Registered 2 months before it started.
• Ran for about 10 months before it stopped.
• 179 participants enrolled.
• No results are posted on the registry.

Vital statistics

Status

Terminated

Phase

Phase 2

Sponsor

Sorrento Therapeutics, Inc.

Sponsor type

Industry

Conditions

Covid19

Interventions

COVI-DROPS; Placebo

Participants

179

Sites

1

Countries

United Kingdom

Trials that died the same way

• Effect of Enzymes on Dental Biofilm Accumulation in Healthy Individuals
  “The study was terminated after interim data analysis” (68% match in meaning)
• Moxonidine in Patients Undergoing Vascular Surgery
  “Study was stopped after pre-definied interim analysis because of no effects” (66% match in meaning)
• Intracoronary Bolus Only Compared With Intravenous Bolus and 12-hours Infusion of Abciximab in Non-ST Elevation Myocardial Infarction.
  “The study was terminated early due to a shortage of research and analytical personnel, which prevented the completion of the study as planned” (65% match in meaning)
• Magrolimab + Azacitidine Versus Azacitidine + Placebo in Untreated Participants With Myelodysplastic Syndrome (MDS)
  “Study discontinued due to futility based on a planned analysis” (65% match in meaning)
• Adherence to Antidepressant Treatment in Subjects With Depression
  “The study was terminated early based on the planned interim analysis that did not meet criteria for continuation.” (65% match in meaning)

Look deeper

• The official registry record (the source of truth)
• Record history: every change the sponsor made
• Open it in the database

Everything here comes from the current ClinicalTrials.gov record. The timeline uses the record’s dates; dates marked planned are the sponsor’s plans. The cause of death is an automatic, unverified label. This is research information, not medical advice.