Autopsy report · NCT04345289

Efficacy and Safety of Novel Treatment Options for Adults With COVID-19 Pneumonia

“DSMB advise due to high probability of futility”

The sponsor’s own words in the registry.

Life of this trial

• Ran for about 10 months before it stopped.
• 147 participants enrolled.
• No results are posted on the registry.

Vital statistics

Status

Terminated

Phase

Phase 3

Sponsor

Thomas Benfield

Sponsor type

University, hospital or other

Conditions

COVID; Corona Virus Infection; Viral Pneumonia

Interventions

Convalescent anti-SARS-CoV-2 plasma; Infusion placebo

Participants

147

Sites

12

Countries

Denmark

Trials that died the same way

• Helping HIV Infected Patients in South Africa Adhere to Drug Regimens
  “DSMB stopped trial for futility” (77% match in meaning)
• Study of Immune Modulatory Drugs and Other Treatments in COVID-19 Patients: Sarilumab, Azithromycin, Hydroxychloroquine Trial - CORIMUNO-19 - VIRO
  “DSMB recommendation (futility)” (73% match in meaning)
• Delayed Cord Clamping and Use of Oxytocin
  “Futility suggested by DSMC” (72% match in meaning)
• Medical Optimization of Management of Type 2 Diabetes Complicating Pregnancy (MOMPOD)
  “Recommendation by the DSMB that the study be stopped for futility” (70% match in meaning)
• A Phase III Trial of Lorenzo's Oil in Adrenomyeloneuropathy
  “Upon recommendation of DSMB” (68% match in meaning)

Look deeper

• The official registry record (the source of truth)
• Record history: every change the sponsor made
• Open it in the database

Everything here comes from the current ClinicalTrials.gov record. The timeline uses the record’s dates; dates marked planned are the sponsor’s plans. The cause of death is an automatic, unverified label. This is research information, not medical advice.