Autopsy report · NCT02932475

Medical Optimization of Management of Type 2 Diabetes Complicating Pregnancy (MOMPOD)

“Recommendation by the DSMB that the study be stopped for futility”

The sponsor’s own words in the registry.

Life of this trial

• Registered 1 year before it started.
• Ran for about 5 years 1 month before it stopped.
• 831 participants enrolled.
• Results were posted on the registry 11 months after it ended.

Vital statistics

Status

Terminated

Phase

Phase 3

Sponsor

University of North Carolina, Chapel Hill

Sponsor type

University, hospital or other

Conditions

Diabetes; Pregnancy

Interventions

Metformin; Placebo

Participants

831

Sites

10

Countries

United States

Trials that died the same way

• ATG Plus Low-dose PT-Cy for GVHD Prevention
  “DSMB recommended halting the study owing to futility after the first interim analysis in August 2024.” (79% match in meaning)
• Direct Lysis of Staph Aureus Resistant Pathogen Trial of Exebacase
  “The independent DSMB recommended that the study be stopped for futility following interim efficacy analysis.” (78% match in meaning)
• Study of Pembrolizumab (MK-3475) Plus Enzalutamide Versus Placebo Plus Enzalutamide in Participants With Metastatic Castration-resistant Prostate Cancer (mCRPC) (MK-3475-641/KEYNOTE-641)
  “The study stopped due to futility” (74% match in meaning)
• Estrogen Replacement to Reduce Risk of Neurologic Injury After Coronary Artery Bypass Graft Surgery
  “DSMB stopped the study based on conclusion of likely futility of treatment on the primary outcome.” (72% match in meaning)
• Comparison Between Radiofrequency and Balloon Compression in the Treatment of Idiopathic Trigeminal Neuralgia
  “Study halted due to futility” (71% match in meaning)

Look deeper

• The official registry record (the source of truth)
• Record history: every change the sponsor made
• Open it in the database

Everything here comes from the current ClinicalTrials.gov record. The timeline uses the record’s dates; dates marked planned are the sponsor’s plans. The cause of death is an automatic, unverified label. This is research information, not medical advice.