Autopsy report · NCT03801356

Threshold Response of Lumbar Selective Nerve Root Block in Predicting Good Outcome Following Lumbar Foraminotomy

“The study was terminated early due to a number of concurrent issues: low enrollment, limited data and COVID-19.”

The sponsor’s own words in the registry.

Life of this trial

• Registered 5 months after it had already started.
• Ran for about 2 years 4 months before it stopped.
• 11 participants enrolled.
• Results were posted on the registry 2 years 7 months after it ended.

Vital statistics

Status

Terminated

Phase

Phase 4

Sponsor

The Cleveland Clinic

Sponsor type

University, hospital or other

Conditions

Back Pain; Radiculopathy Lumbar; Degenerative Lumbar Spinal Stenosis

Interventions

Selective Nerve Root Block

Participants

11

Sites

1

Countries

United States

Trials that died the same way

• Evaluating Emetine for Viral Outbreaks (EVOLVE)
  “The study was terminated due to insufficient participant enrollment resulting from a lower-than-expected number of COVID-19 cases” (86% match in meaning)
• A Study of Deflazacort (Emflaza®) in Participants With Limb-Girdle Muscular Dystrophy 2I (LGMD2I)
  “The study was terminated early due to low enrollment and missing efficacy assessment data due to missed visits related to COVID-19.” (85% match in meaning)
• Anti-RSV Study in Chinese Patients (ASCENT)
  “The study was terminated early due to COVID-19-related enrollment disruptions, not as a result of any product safety concerns.” (83% match in meaning)
• Peripheral Nerve Stimulation for Back
  “Due to COVID-19 and other factors this study was terminated early and the patients currently enrolled are being used as a small pilot study.” (82% match in meaning)
• A Study to Assess the Impact of Omalizumab on Exercise Capacity, Physical Activity, and Sleep Quality in Participants With Moderate to Severe Allergic Asthma
  “Due to low enrollment, this study was terminated early.” (82% match in meaning)

Look deeper

• The official registry record (the source of truth)
• Record history: every change the sponsor made
• Open it in the database

Everything here comes from the current ClinicalTrials.gov record. The timeline uses the record’s dates; dates marked planned are the sponsor’s plans. The cause of death is an automatic, unverified label. This is research information, not medical advice.