The Cleveland Clinic

Why trials sponsored by The Cleveland Clinic stopped, in this sample of ClinicalTrials.gov.

30 stopped trials with a clear reason; 87% ended for non-scientific reasons.

Trials

• Vasopressin Hemodynamic Response as a Septic Shock Subphenotype Indicator
  NCT06426407 · TERMINATED · slow accrual
  “The study was terminated due to lack of feasibility.”
• Validation of the SentiCor-300 Continuous Noninvasive Blood Pressure
  NCT05625256 · WITHDRAWN · funding business
  “Funding”
• Surgical Outcomes Following Neurectomy Based Upon Response to Local Anesthetic Injection in Chronic Groin Pain
  NCT05386693 · TERMINATED · slow accrual
  “Low enrollment”
• Operative vs Non-Operative Management of Acute Appendicitis and Acute Cholecystitis in COVID-19 Positive Patients
  NCT04748120 · TERMINATED · slow accrual
  “Insufficient eligible patients”
• Correlation Between Peripheral Venous Pressure and Central Venous Pressure in the Cardiac Intensive Care Unit
  NCT03526497 · TERMINATED · slow accrual
  “Poor enrollment”
• The Role of F-18 Florbetapir in the Early Detection of Cardiac Amyloidosis
  NCT03040427 · TERMINATED · slow accrual
  “Low enrollment”
• Catheter Ablation vs. Medical Therapy in Congested Hearts With AF
  NCT02686749 · TERMINATED · slow accrual
  “unable to reach enrollment goal”
• Frequency of Reduced Leaflet Motion After Surgical Aortic Valve Replacement and Transcatheter Aortic Valve Replacement.
  NCT02696226 · TERMINATED · slow accrual
  “Poor enrollment”
• Optimal Positioning of Nasopharyngeal Temperature Probes
  NCT02993003 · WITHDRAWN · slow accrual
  “No enrollment”
• WarmSmart Warming Protocol
  NCT02812069 · WITHDRAWN · safety
  “Safety issue”
• Intraoperative Anesthesia Care Transition Checklist
  NCT02453828 · TERMINATED · logistics pi
  “PI has requested for this study be closed due to technical issues”
• SO+IUI After Operative Laparoscopy in Patients With Advanced Stage Endometriosis
  NCT02520505 · WITHDRAWN · slow accrual
  “no participants enrolled”
• Intralesional Tetracycline Injection in the Treatment of Chalazia
  NCT01763437 · WITHDRAWN · logistics pi
  “Investigator left the institution”
• TRACER RGD-K5 Carotid Plaque Imaging Study
  NCT01968226 · TERMINATED · logistics pi
  “Investigator left instititution”
• Weight Regain Study After Bariatric Surgery-A Pilot Project
  NCT02754453 · WITHDRAWN · funding business
  “No funding”
• Trial of Cooling for Patients With Excel Cryo Cooling System in Intracerebral Hemorrhage (ICH)
  NCT01933230 · TERMINATED · slow accrual
  “Closed due to issues encountered with meeting enrollment goals at our site.”
• The Impact of Triptan and Doxycycline on Neuroinflammatory Biomarkers in Acute Migraine
  NCT01653522 · WITHDRAWN · slow accrual
  “No participants enrolled”
• Rhythmic Auditory Stimulation and Walking Performance in Multiple Sclerosis (MS) Patients
  NCT01086371 · WITHDRAWN · other
  “Study being redesigned in anticipation of new study protocol.”
• Switching From Efavirenz to Atazanavir/ Ritonavir in HIV-infected Subjects With Good Virologic Suppression
  NCT01194856 · TERMINATED · slow accrual
  “Closed due to low enrollment”
• Effect of Bispectral Index (BIS) Titrated Propofol Sedation on Lower Esophageal Sphincter Pressures and Esophageal Function in Intensive Care Patients
  NCT01173263 · TERMINATED · slow accrual
  “recruitment difficulties”
• Effect of Nortriptyline on Abdominal Pain/Discomfort and Quality of Life in Patients With Nonulcer Dyspepsia
  NCT00547703 · TERMINATED · slow accrual
  “Not enough participants - only 5 since the study started”
• Regional Anesthesia in Colon Rectal Surgery
  NCT00684229 · WITHDRAWN · slow accrual
  “investigator could not identify any patients”
• Pilot Study of Inhaled Nitric Oxide to Treat Pulmonary Insufficiency in Congenital Heart Disease
  NCT00543933 · TERMINATED · logistics pi
  “Investigator left institution”
• FIRE-PAD: Functional Improvement Through Revascularization of the Extremities for Peripheral Arterial Disease
  NCT00274157 · TERMINATED · slow accrual
  “Low enrollment”
• Effect of Bedrest With and Without Exercise on the Heart
  NCT00598494 · TERMINATED · logistics pi
  “Main bedrest study moved to Texas. No enrollment at Cleveland Clinic.”
• Discoid Lupus Erythematosus of the Scalp and a Trial of Biologic Therapy With Raptiva
  NCT00308204 · WITHDRAWN · slow accrual
  “inadequate number of enrolled study subjects”
• NORDIC: Nitric Oxide-Derived Oxidants and Regional Endothelial and Diastolic Dysfunction in Dilated Cardiomyopathy
  NCT00293137 · TERMINATED · safety
  “safety concerns regarding use of rosiglitazone”
• Three Dimensional Imaging and Wireless Technologies to Enhance Medical Care in Space
  NCT00598767 · TERMINATED · funding business
  “funding issues”
• Diagnostic Three Dimensional Echocardiography Study Protocol
  NCT00598754 · WITHDRAWN · funding business
  “Funding issues”
• The Effect of Lipitor on Aortic Stenosis
  NCT00590135 · TERMINATED · futility
  “Poor Reducibility - primary endpoint measure not obtainable”

Reasons are labeled automatically and are unverified. See the methodology. This is research information, not medical advice. Search the full database.