Autopsy report · NCT03755362

Dental Carotid Cognitive Study

“The COVID-19 pandemic has disrupted the investigators ability to continue this study. Follow-up visits were missed to the COVID-19 pandemic restrictions. The investigator has elected to close enrollment and stop follow-up visits.”

The sponsor’s own words in the registry.

Life of this trial

• Registered 5 months before it started.
• Ran for about 1 year 11 months before it stopped.
• 26 participants enrolled.
• No results are posted on the registry.

Vital statistics

Status

Terminated

Phase

Na

Sponsor

University of Maryland, Baltimore

Sponsor type

University, hospital or other

Conditions

Carotid Stenosis; Mild Cognitive Impairment; Periodontitis

Interventions

Standard Treatment; Intensive Treatment

Participants

26

Sites

1

Countries

United States

Trials that died the same way

• Intranasal Insulin for the Treatment of HAND
  “On 3/15/2020 study visits were suspended due to COVID-19 pandemic. With safety concerns surrounding COVID-19 and difficulty recruiting, the investigators decided to close enrollment 10/16/2020 after interim data were reviewed by the DSMB and NIH.” (74% match in meaning)
• Riociguat in Patients With Operable CTEPH Prior to Pulmonary Endarterectomy (PEA Bridging Study)
  “The study was stopped due to slower than expected recruitment and the additional limitations on clinical research imposed by the COVID-19 pandemic, both of which made study completion within a reasonable timeframe appear unlikely.” (73% match in meaning)
• Study of Focal Airway Disease in Asthma Using Image Guided Bronchoscopy
  “The restrictions on research imposed for the COVID-19 pandemic prevented us from launching study recruitment and visits. At this stage our funding is not sufficient to allow us to enroll sufficient numbers of patients so we will close the study.” (72% match in meaning)
• Zambia Common Elements Treatment Approach Pilot Study
  “COVID-19 precluded the study team from being able to complete all follow-up assessments.The study was halted on March 17, 2020 and did not resume.” (71% match in meaning)
• Spinal Anesthesia in Total Hip Arthroplasty
  “This study was terminated due to pressing matters related to the COVID-19 pandemic - staff shortages and changes of personnel, data gaps due to the pandemic, participants not being able to continue follow-up visits, and ongoing enrollment issues.” (71% match in meaning)

Look deeper

• The official registry record (the source of truth)
• Record history: every change the sponsor made
• Open it in the database

Everything here comes from the current ClinicalTrials.gov record. The timeline uses the record’s dates; dates marked planned are the sponsor’s plans. The cause of death is an automatic, unverified label. This is research information, not medical advice.