Autopsy report · NCT02807597

Real-time Intraoperative Breast Cancer Visualization for Margin Assessment

“Before LS301's licensing and reformulation, 9 patients received LS301-HSA (Phase 1a) , but since no patients were recruited (in Phase 1b) before the product expired, this study has been terminated.”

The sponsor’s own words in the registry.

Life of this trial

• Registered 3 years 8 months before it started.
• Ran for about 1 year 11 months before it stopped.
• 9 participants enrolled.
• Results were posted on the registry 3 years 7 months after it ended.

Vital statistics

Status

Terminated

Phase

Phase 1, Phase 2

Sponsor

Samuel Achilefu

Sponsor type

University, hospital or other

Conditions

Breast Cancer; Cancer of the Breast

Interventions

LS301; Cancer Vision Goggles and standard fluorescence imaging systems; Surgery

Participants

9

Sites

1

Countries

United States

Trials that died the same way

• A Study of [14C]-LY3023703 in Healthy Participants
  “Due to safety results from another trial of LY3023703. No participants in this study received study drug.” (62% match in meaning)
• Study of Ruxolitinib (INCB018424) Administered Orally to Patients With Androgen Independent Metastatic Prostate Cancer
  “According to the protocol, the sponsor terminated the study after it was determined that less than 2 of the first 22 patients showed a PSA50 response.” (59% match in meaning)
• Evaluation of Revumenib in Participants With Colorectal Cancer and Other Solid Tumors
  “Study was terminated by sponsor after Phase 1b as pre-defined signals of efficacy were not met in the Phase 1b dose expansion cohort.” (58% match in meaning)
• A Long-Term Safety And Tolerability Study Of Bapineuzumab In Alzheimer Disease Patients
  “The study was terminated on August 6, 2012, because 2 large Phase 3 studies showed no clinical benefit. This decision was not based on any new safety concerns.” (57% match in meaning)
• Nab-Sirolimus and Pazopanib Hydrochloride in Treating Patients With Advanced Nonadipocytic Soft Tissue Sarcomas
  “Study was terminated at completion of the Phase 1 dose escalation due to loss of financial support.” (56% match in meaning)

Look deeper

• The official registry record (the source of truth)
• Record history: every change the sponsor made
• Open it in the database

Everything here comes from the current ClinicalTrials.gov record. The timeline uses the record’s dates; dates marked planned are the sponsor’s plans. The cause of death is an automatic, unverified label. This is research information, not medical advice.