Autopsy report · NCT02480010

A Study of Pertuzumab in Participants With Prostate Cancer

“The study was terminated at the time of interim analysis since none of the participants showed a PSA response.”

The sponsor’s own words in the registry.

Life of this trial

• Registered 11 years 9 months after it had already started.
• Ran for about 2 years before it stopped.
• 68 participants enrolled.
• Results were posted on the registry 10 years after it ended.

Vital statistics

Status

Terminated

Phase

Phase 2

Sponsor

Hoffmann-La Roche

Sponsor type

Industry

Conditions

Prostate Cancer

Interventions

Pertuzumab

Participants

68

Sites

11

Countries

France, Germany, Italy, Netherlands, Spain, United Kingdom

Trials that died the same way

• Study of Pemetrexed for Second-Line Pancreas Cancer
  “At interim analysis the study did not meet the response criteria to continue” (77% match in meaning)
• Adherence to Antidepressant Treatment in Subjects With Depression
  “The study was terminated early based on the planned interim analysis that did not meet criteria for continuation.” (77% match in meaning)
• Study Evaluating PPM-204 In Subjects With Type 2 Diabetes
  “Study terminated as a result of interim analysis not meeting predetermined criteria.” (75% match in meaning)
• Effect of Enzymes on Dental Biofilm Accumulation in Healthy Individuals
  “The study was terminated after interim data analysis” (74% match in meaning)
• A Study to Evaluate the Efficacy and Safety of Piracetam on Aphasia After Acute Ischemic Cerebral Artery Stroke
  “This study was terminated after a pre-specified interim analysis. Please see Detailed Study Description for further information.” (73% match in meaning)

Look deeper

• The official registry record (the source of truth)
• Record history: every change the sponsor made
• Open it in the database

Everything here comes from the current ClinicalTrials.gov record. The timeline uses the record’s dates; dates marked planned are the sponsor’s plans. The cause of death is an automatic, unverified label. This is research information, not medical advice.