Autopsy report · NCT00425919

Study Evaluating PPM-204 In Subjects With Type 2 Diabetes

“Study terminated as a result of interim analysis not meeting predetermined criteria.”

The sponsor’s own words in the registry.

Life of this trial

• Ran for about 9 months before it stopped.
• 500 participants enrolled.
• No results are posted on the registry.

Vital statistics

Status

Terminated

Phase

Phase 2

Sponsor

Wyeth is now a wholly owned subsidiary of Pfizer

Sponsor type

Industry

Conditions

Diabetes Mellitus

Interventions

PPM-204

Participants

500

Sites

68

Countries

Argentina, Australia, Brazil, Canada, China, Croatia, Greece, Hong Kong, India, Italy, Mexico, Romania and more

Trials that died the same way

• Adherence to Antidepressant Treatment in Subjects With Depression
  “The study was terminated early based on the planned interim analysis that did not meet criteria for continuation.” (91% match in meaning)
• Effect of Enzymes on Dental Biofilm Accumulation in Healthy Individuals
  “The study was terminated after interim data analysis” (86% match in meaning)
• Linifanib in Treating Patients With Advanced, Refractory Colorectal Cancer
  “Interim analysis determined the study did not meet criteria to proceed” (85% match in meaning)
• A Comparison of Surgical Preparations and Wound Infection Rates for Elective Cesarean Sections
  “Study was stopped following interim analysis.” (84% match in meaning)
• Study of Pemetrexed for Second-Line Pancreas Cancer
  “At interim analysis the study did not meet the response criteria to continue” (83% match in meaning)

Look deeper

• The official registry record (the source of truth)
• Record history: every change the sponsor made
• Open it in the database

Everything here comes from the current ClinicalTrials.gov record. The timeline uses the record’s dates; dates marked planned are the sponsor’s plans. The cause of death is an automatic, unverified label. This is research information, not medical advice.