Autopsy report · NCT02175576

Randomized Controlled Clinical Outcomes of the Vanguard XP Bicruciate Knee System

“Data no longer required to meet regulatory requirements.”

The sponsor’s own words in the registry.

Life of this trial

• Registered 4 months before it started.
• Ran for about 6 years 2 months before it stopped.
• 50 participants enrolled.
• Results were posted on the registry 2 years 2 months after it ended.

Vital statistics

Status

Terminated

Phase

Na

Sponsor

Zimmer Biomet

Sponsor type

Industry

Conditions

Osteoarthritis; Rheumatoid Arthritis; Traumatic Arthritis; Lower Limb Deformity; Post-traumatic Deformity; Complications, Arthroplasty

Interventions

Vanguard XP Bicruciate Knee System; Vanguard CR Knee System

Participants

50

Sites

2

Countries

United States

Trials that died the same way

• Safety, Pharmacokinetics and Antitumor Activity of BGB-B167 Alone and in Combination With Tislelizumab in Participants With Solid Tumors in Chinese Participants
  “Sponsor determined the data was no longer needed.” (77% match in meaning)
• Bioavailability of Pancreatic Enzymes in the Human Upper Intestine (Duodenum and Jejunum)
  “No longer required study by FDA for NDA approval.” (65% match in meaning)
• MRI-Guided LITT for Treatment Metastatic Brain Tumors
  “PI change and no enrollment ever, therefore no data available.” (59% match in meaning)
• ROSA® Hip System THA PMCF
  “The data needed for regulatory submissions based on the current pace of the study, will not be available in the foreseeable future.” (59% match in meaning)
• A Long Term Follow up Study for Patients Who Previously Took Part in the Phase I Study IMM-101-001
  “Sponsor considered no further meaningful data was being collected, nor were likely to be collected in the future.” (59% match in meaning)

Look deeper

• The official registry record (the source of truth)
• Record history: every change the sponsor made
• Open it in the database

Everything here comes from the current ClinicalTrials.gov record. The timeline uses the record’s dates; dates marked planned are the sponsor’s plans. The cause of death is an automatic, unverified label. This is research information, not medical advice.