Autopsy report · NCT02066311

Nelfinavir in Systemic Lupus Erythematosus

“Stage 1 terminated 6/1/18 prior to completion of Stage 1 due to low enrollment and efficacy”

The sponsor’s own words in the registry.

Life of this trial

• Registered 7 months before it started.
• Ran for about 3 years 9 months before it stopped.
• 15 participants enrolled.
• Results were posted on the registry 1 year 8 months after it ended.

Vital statistics

Status

Terminated

Phase

Phase 2

Sponsor

Northwell Health

Sponsor type

University, hospital or other

Conditions

Systemic Lupus Erythematosus

Interventions

Nelfinavir

Participants

15

Sites

8

Countries

United States

Trials that died the same way

• Efficacy and Safety of MK-7622 as Adjunct Therapy in Participants With Alzheimer's Disease (MK-7622-012)
  “Stage 1 interim analysis of efficacy met the criteria for early trial termination (futility). The trial was terminated at Stage 1; did not proceed to Stage 2.” (74% match in meaning)
• Evaluation of Revumenib in Participants With Colorectal Cancer and Other Solid Tumors
  “Study was terminated by sponsor after Phase 1b as pre-defined signals of efficacy were not met in the Phase 1b dose expansion cohort.” (65% match in meaning)
• Efficacy and Tolerability of Deucravacitinib in the Management of Palmoplantar Pustulosis
  “Terminated early due to lack of expected efficacy. Three participants were enrolled but none completed the study.” (63% match in meaning)
• Treatment of West Nile Virus With MGAWN1
  “Early termination due to the inability to enroll (13 of 120 subjects enrolled)” (62% match in meaning)
• Nab-Sirolimus and Pazopanib Hydrochloride in Treating Patients With Advanced Nonadipocytic Soft Tissue Sarcomas
  “Study was terminated at completion of the Phase 1 dose escalation due to loss of financial support.” (62% match in meaning)

Look deeper

• The official registry record (the source of truth)
• Record history: every change the sponsor made
• Open it in the database

Everything here comes from the current ClinicalTrials.gov record. The timeline uses the record’s dates; dates marked planned are the sponsor’s plans. The cause of death is an automatic, unverified label. This is research information, not medical advice.