Autopsy report · NCT00927953

Treatment of West Nile Virus With MGAWN1

“Early termination due to the inability to enroll (13 of 120 subjects enrolled)”

The sponsor’s own words in the registry.

Life of this trial

• Registered 1 month after it had already started.
• Ran for about 2 years before it stopped.
• 13 participants enrolled.
• Results were posted on the registry 1 year 6 months after it ended.

Vital statistics

Status

Terminated

Phase

Phase 2

Sponsor

MacroGenics

Sponsor type

Industry

Conditions

West Nile Neuroinvasive Disease; West Nile Virus Infection; Encephalitis; Meningitis; Acute Flaccid Paralysis; West Nile Fever

Interventions

MGAWN1; Placebo - normal saline

Participants

13

Trials that died the same way

• A Study to Evaluate Lumasiran in Adults With Recurrent Calcium Oxalate Kidney Stone Disease and Elevated Urinary Oxalate Levels
  “Study terminated early due to low enrollment” (77% match in meaning)
• Allogeneic Stem Cell Transplant After ATG, High-Dose Melphalan, and Fludarabine for Patients With Breast Cancer
  “Terminated early due to poor enrollment” (76% match in meaning)
• Digital Therapeutic vs Educational App for Depression Among Adolescents
  “Terminated due to difficulty enrolling patients in the proposed time frame” (75% match in meaning)
• Safety Study of GMA161 in Patients With Idiopathic Thrombocytopenic Purpura (ITP)
  “Study terminated due to low enrollment.” (75% match in meaning)
• Effect of Pradaxa vs Warfarin on Bone Mass and Bone Turnover Markers
  “Study was terminated early due to low enrollment numbers.” (75% match in meaning)

Look deeper

• The official registry record (the source of truth)
• Record history: every change the sponsor made
• Open it in the database

Everything here comes from the current ClinicalTrials.gov record. The timeline uses the record’s dates; dates marked planned are the sponsor’s plans. The cause of death is an automatic, unverified label. This is research information, not medical advice.