Autopsy report · NCT02050321

A Phase II Study of Vemurafenib Combined With Acitretin in Patients With Advanced Melanoma

“Pharmaceutical company pulled support for the trial.”

The sponsor’s own words in the registry.

Life of this trial

• Registered 1 month after it had already started.
• Ran for about 1 year 7 months before it stopped.
• 2 participants enrolled.
• Results were posted on the registry 1 year 9 months after it ended.

Vital statistics

Status

Terminated

Phase

Phase 2

Sponsor

University of Arizona

Sponsor type

University, hospital or other

Conditions

Malignant Melanoma

Interventions

Acitretin; Vemurafenib

Participants

2

Sites

1

Countries

United States

Trials that died the same way

• 2321GCCC: CRD3874-SI in Patients With Relapsed/Refractory AML
  “Pharmaceutical Company withdrew support and investigational product” (72% match in meaning)
• Aflibercept for Retinopathy in the Real World
  “Superceded by a larger trial by the pharmaceutical company” (71% match in meaning)
• A Study of the Safety and Pharmacokinetics of AGS-8M4 Given in Combination With Chemotherapy in Women With Ovarian Cancer
  “Trial was terminated to allow sponsors to evaluate the future development of the drug program” (69% match in meaning)
• A Phase 2 Study of Intravitreal AVD-104 in Diabetic Macular Edema
  “The trial was stopped early due to insufficient study drug supply and study funding constraints” (69% match in meaning)
• A Clinical Study to Compare the Efficacy and Safety of HLX10 in Combination With HLX04 Versus Sorafenib as the First-line Treatment in Patients With Locally Advanced or Metastatic HCC
  “The trial used sorafenib as a control drug. It's not suitable now(after the A+T has been approved).The sponsor terminated the trial.” (68% match in meaning)

Look deeper

• The official registry record (the source of truth)
• Record history: every change the sponsor made
• Open it in the database

Everything here comes from the current ClinicalTrials.gov record. The timeline uses the record’s dates; dates marked planned are the sponsor’s plans. The cause of death is an automatic, unverified label. This is research information, not medical advice.