Autopsy report · NCT01903187

EnligHTN IV Trial - Multicenter Sham-controlled RCT of Renal Denervation for Hypertension

“There were no safety or effectiveness concerns. There were concerns about completing enrollment due to a competitive device's potential approval.”

The sponsor’s own words in the registry.

Life of this trial

• Registered 3 months before it started.
• Ran for about 3 years 1 month before it stopped.
• 4 participants enrolled.
• Results were posted on the registry.

Vital statistics

Status

Terminated

Phase

Na

Sponsor

Abbott Medical Devices

Sponsor type

Industry

Conditions

Hypertension

Interventions

EnligHTN Renal Denervation; Sham

Participants

4

Sites

3

Countries

United States

Trials that died the same way

• Study of the Efficacy and Safety of Parsaclisib in Participants With Primary Warm Autoimmune Hemolytic Anemia
  “A business decision was made to discontinue further enrollment. There were no safety concerns that contributed to this decision.” (81% match in meaning)
• A Study of TAK-659 in Combination With Bendamustine (+/-Rituximab), Gemcitabine, Lenalidomide, or Ibrutinib for the Treatment of Participants With Advanced Non-Hodgkin Lymphoma
  “Business decision, insufficient enrollment, no safety or efficacy concerns.” (76% match in meaning)
• A Study to Evaluate INCB177054 in Participants With Select Advanced or Metastatic Solid Tumors
  “This was a strategic business decision. There were no safety concerns contributing to this decision.” (72% match in meaning)
• A Safety Study of IV Stem Cell-derived Extracellular Vesicles (UNEX-42) in Preterm Neonates at High Risk for BPD
  “The study was discontinued due to a business decision; no safety concerns were noted.” (67% match in meaning)
• Safety and Efficacy of Cryoablation Combined With Radiation Therapy for the Palliation of Painful Bone Metastases
  “No patients were treated due to enrollment challenges.” (65% match in meaning)

Look deeper

• The official registry record (the source of truth)
• Record history: every change the sponsor made
• Open it in the database

Everything here comes from the current ClinicalTrials.gov record. The timeline uses the record’s dates; dates marked planned are the sponsor’s plans. The cause of death is an automatic, unverified label. This is research information, not medical advice.