Autopsy report · NCT01685840

Guiding Evidence Based Therapy Using Biomarker Intensified Treatment

“Project was stopped due to futility”

The sponsor’s own words in the registry.

Life of this trial

• Registered 3 months before it started.
• Ran for about 3 years 9 months before it stopped.
• 894 participants enrolled.
• Results were posted on the registry 1 year 3 months after it ended.

Vital statistics

Status

Terminated

Phase

Na

Sponsor

Duke University

Sponsor type

University, hospital or other

Conditions

Heart Failure

Interventions

Usual Care; Biomarker-guided care NT-proBNP

Participants

894

Sites

46

Countries

Canada, United States

Trials that died the same way

• Comparison Between Radiofrequency and Balloon Compression in the Treatment of Idiopathic Trigeminal Neuralgia
  “Study halted due to futility” (69% match in meaning)
• Prevention of Unexplained Recurrent Abortion by Enoxaparine
  “Stopped for futility” (68% match in meaning)
• Pembrolizumab (MK-3475) Versus Placebo Following Surgery and Radiation in Participants With Locally Advanced Cutaneous Squamous Cell Carcinoma (MK-3475-630/KEYNOTE-630)
  “The study stopped due to futility” (66% match in meaning)
• Evaluation of Hydrocortisone, Vitamin C and Thiamine for the Treatment of Septic Shock
  “The research is no longer funded and terminated due to futility” (66% match in meaning)
• Aspirin Resistance Following Coronary Bypass Surgery
  “The researcher had left the hospital and the project was stopped” (66% match in meaning)

Look deeper

• The official registry record (the source of truth)
• Record history: every change the sponsor made
• Open it in the database

Everything here comes from the current ClinicalTrials.gov record. The timeline uses the record’s dates; dates marked planned are the sponsor’s plans. The cause of death is an automatic, unverified label. This is research information, not medical advice.