Autopsy report · NCT01583881

Denervation of the renAl sympathetIc nerveS in hearT Failure With nOrmal Lv Ejection Fraction

“Slow inclusion”

The sponsor’s own words in the registry.

Life of this trial

• Ran for about 4 years 3 months before it stopped.
• 60 participants planned (an estimate, not an actual count).
• No results are posted on the registry.

Vital statistics

Status

Terminated

Phase

Phase 2, Phase 3

Sponsor

UMC Utrecht

Sponsor type

University, hospital or other

Conditions

Diastolic Heart Failure; Hypertension

Interventions

renal denervation

Participants

60 (planned, not actual)

Sites

2

Countries

Netherlands

Trials that died the same way

• Cutting Balloon Versus Non-cutting Balloon for the Treatment of Venous Stenosis in the Fistulas of Hemodialyzed Patients
  “Inclusion curve too slow.” (77% match in meaning)
• PET / CT With 18F-FDG: Does it Optimize the I 123-MIBG Imaging Results in the Search for Discriminating Factors for the Implementation of an Implantable Defibrillator?
  “Inclusion rate too slow / infeasible.” (75% match in meaning)
• Comparison of Two Treatment Strategies in Patients With an Acute Coronary Syndrome Without ST Elevation
  “Because of inclusion delay” (71% match in meaning)
• Biochemical Makers for Outcome After Pediatric out-of Hospital Cardiac Arrest
  “Low inclusion rate” (70% match in meaning)
• Tamsulosin for Urinary Retention in Hospitalized Older Women
  “low inclusion” (69% match in meaning)

Look deeper

• The official registry record (the source of truth)
• Record history: every change the sponsor made
• Open it in the database

Everything here comes from the current ClinicalTrials.gov record. The timeline uses the record’s dates; dates marked planned are the sponsor’s plans. The cause of death is an automatic, unverified label. This is research information, not medical advice.