Autopsy report · NCT01355523

The Effect of Melatonin on Depression, Anxiety, Cognitive Function and Sleep Disturbances in Breast Cancer Patients

“Inclusion rate not as expected. Not financially possible to involve other centres.”

The sponsor’s own words in the registry.

Life of this trial

• Registered 2 months before it started.
• Ran for about 1 year 6 months before it stopped.
• 54 participants enrolled.
• Results were posted on the registry 1 year 4 months after it ended.

Vital statistics

Status

Terminated

Phase

Phase 2, Phase 3

Sponsor

Melissa Voigt Hansen

Sponsor type

University, hospital or other

Conditions

Breast Cancer; Depression

Interventions

Melatonin (N-acetyl-5-methoxytryptamine); Placebo

Participants

54

Sites

1

Countries

Denmark

Trials that died the same way

• Dexmedetomidine Pharmacokinetics-pharmacodynamics in Mechanically Ventilated Children With Single-organ Respiratory Failure
  “Poor inclusion rate.” (71% match in meaning)
• Contrast Enhanced Sonothrombolysis and Sonolysis in Stroke - a Swedish Study (CE-5S)
  “Poor inclusion rate \& lack of funding” (69% match in meaning)
• Didgeridoo Treatment to Improve Pharyngeal Compliance in Obstructive Sleep Apnea-hypopnea Syndrome in Children
  “no inclusion since the opening of the centers (difficulties in recruiting staff which impact the functioning of the services)” (67% match in meaning)
• Randomized Clinical Trial to Assess the Efficacy and Safety of Concomitant Use of Rifampicin and Efavirenz 600 X 800mg
  “Lack of financial support and low inclusion rate” (67% match in meaning)
• Cetrotide Treatment Optimization
  “Due to limited rate of patient inclusion” (64% match in meaning)

Look deeper

• The official registry record (the source of truth)
• Record history: every change the sponsor made
• Open it in the database

Everything here comes from the current ClinicalTrials.gov record. The timeline uses the record’s dates; dates marked planned are the sponsor’s plans. The cause of death is an automatic, unverified label. This is research information, not medical advice.