Autopsy report · NCT00289081

Primary TKA Cruciate Retaining vs Cruciate Substituting With Rotating Platform Knee Prostheses

“Business reasons”

The sponsor’s own words in the registry.

Life of this trial

• Registered 5 years after it had already started.
• Ran for about 5 years 4 months before it stopped.
• 399 participants enrolled.
• No results are posted on the registry.

Vital statistics

Status

Terminated

Phase

Na

Sponsor

DePuy Orthopaedics

Sponsor type

Industry

Conditions

Osteoarthritis; Arthritis, Rheumatoid; Avascular Necrosis of Bone; Post-traumatic Arthritis; Rheumatoid Arthritis

Interventions

Total Knee Replacement; Total knee replacement

Participants

399

Sites

4

Countries

United States

Trials that died the same way

• PS101-mediated ACT With Chemotherapy in Liver Metastases From Cancer of Gastrointestinal Origin
  “Business reason” (94% match in meaning)
• Safety, Immune and Tumor Response to a Multi-component Immune Based Therapy (MKC1106-MT) for Patients With Melanoma
  “Financial/Business Reasons” (88% match in meaning)
• First-in-Human Evaluation of GRN-300 in Subjects With Recurrent Ovarian, Primary Peritoneal, and Fallopian Tube Cancers.
  “Business/Commercial Reasons” (87% match in meaning)
• Effect of Timing of Tumor-Treating Fields Plus Short-Course Radiation
  “Organizational reasons” (85% match in meaning)
• Study of Azeliragon in Patients With Mild Alzheimer's Disease and Impaired Glucose Tolerance
  “for business reasons” (82% match in meaning)

Look deeper

• The official registry record (the source of truth)
• Record history: every change the sponsor made
• Open it in the database

Everything here comes from the current ClinicalTrials.gov record. The timeline uses the record’s dates; dates marked planned are the sponsor’s plans. The cause of death is an automatic, unverified label. This is research information, not medical advice.