Autopsy report · NCT06965881

Study to Evaluate the Pharmacokinetics and Safety Effects Following Coadministration of Carbamazepine or Itraconazole With Radiprodil in Healthy Adults

“Study was terminated due to the lack of operational capabilities of the sites to segregate participants as needed.”

The sponsor’s own words in the registry.

Life of this trial

• Ran for about 2 months before it stopped.
• 30 participants enrolled.
• No results are posted on the registry.

Vital statistics

Status

Terminated

Phase

Phase 1

Sponsor

GRIN Therapeutics, Inc.

Sponsor type

Industry

Conditions

Tuberous Sclerosis Complex (TSC); Focal Cortical Dysplasia; Other Neurological Disorders

Interventions

Radiprodil with Carbamazepine; Radiprodil with Itraconazole

Participants

30

Sites

2

Countries

Australia

Trials that died the same way

• Starting the Conversation
  “The study was terminated due to a small number of study participants.” (79% match in meaning)
• Vaginal Estradiol Use in Pessary Care
  “There is a lack of potential study participants at our study site that would meet inclusion criteria, therefore, the study is not feasible and is being terminated.” (79% match in meaning)
• To Determine the Objective Response Rate of 4 Cycles of Docetaxel + Anthracycline (Epirubicin or Doxorubicine) Followed by 4 Cycles of Docetaxel Single Agent
  “the study was early terminated due to lack of recruitment.” (78% match in meaning)
• The Role of Splinting in Fingertip Injuries
  “Very few subjects were enrolled. Therefore, the study was terminated.” (77% match in meaning)
• Dilute Bleach Baths in Pediatric Patients With Atopic Dermatitis
  “the study was terminated due to participant drop out” (77% match in meaning)

Look deeper

• The official registry record (the source of truth)
• Record history: every change the sponsor made
• Open it in the database

Everything here comes from the current ClinicalTrials.gov record. The timeline uses the record’s dates; dates marked planned are the sponsor’s plans. The cause of death is an automatic, unverified label. This is research information, not medical advice.