Autopsy report · NCT05458375

Vaginal Estradiol Use in Pessary Care

“There is a lack of potential study participants at our study site that would meet inclusion criteria, therefore, the study is not feasible and is being terminated.”

The sponsor’s own words in the registry.

Life of this trial

• Registered 6 months before it started.
• Ran for about 4 months before it stopped.
• 11 participants enrolled.
• No results are posted on the registry.

Vital statistics

Status

Terminated

Phase

Early Phase 1

Sponsor

University of South Florida

Sponsor type

University, hospital or other

Conditions

Pelvic Organ Prolapse; Urinary Incontinence; Pessary Ulcer of Vagina; Vaginal Atrophy

Interventions

Estradiol vaginal cream

Participants

11

Sites

1

Countries

United States

Trials that died the same way

• Study to Evaluate the Pharmacokinetics and Safety Effects Following Coadministration of Carbamazepine or Itraconazole With Radiprodil in Healthy Adults
  “Study was terminated due to the lack of operational capabilities of the sites to segregate participants as needed.” (79% match in meaning)
• Efficacy Study of Fluconazole to Treat Coccidioidomycosis Pneumonia (Valley Fever)
  “Study terminated due to lack of feasibility of study design.” (78% match in meaning)
• Triple vs High Dose Inhaled CORticosteroids
  “The study is closed due to lack of recruitment.” (74% match in meaning)
• Self-Management Of Asthma By Forced Oscillation Technique
  “The study was terminated early due to an unexpected difficulty at the study sites in recruiting patients who met all the inclusion criteria.” (74% match in meaning)
• Bilateral Versus Unilateral Strength Training After ACLR
  “This study is withdrawn due to a lack of available recruitment within the researchers' timeframe.” (74% match in meaning)

Look deeper

• The official registry record (the source of truth)
• Record history: every change the sponsor made
• Open it in the database

Everything here comes from the current ClinicalTrials.gov record. The timeline uses the record’s dates; dates marked planned are the sponsor’s plans. The cause of death is an automatic, unverified label. This is research information, not medical advice.