Autopsy report · NCT06703216

Pre-emptive Anakinra for Cytokine Event Reduction

“The trial has been stopped pending FDA approval of modifications to the trial protocol.”

The sponsor’s own words in the registry.

Life of this trial

• Withdrawn before it enrolled anyone. Its dates are the sponsor's plans, not events that happened.

Vital statistics

Status

Withdrawn

Phase

Phase 1, Phase 2

Sponsor

Kevin McNerney

Sponsor type

University, hospital or other

Conditions

B-Acute Lymphoblastic Leukemia; CAR-T Cell Therapy; Cytokine Release Syndrome; Immune Effector Cell Associated Neurotoxicity Syndrome; Immune Effector Cell Associated Hemophagocytic Lymphohistiocytosis-like Syndrome

Interventions

Anakinra (Kineret®)

Participants

0

Sites

1

Countries

United States

Trials that died the same way

• An Extension of Protocol PRO 140_CD01 Study
  “FDA required the sponsor to halt enrollment in the trial and transition participants to available therapies for the treatment of their disease. The trial was subsequently terminated once participants were transitioned.” (75% match in meaning)
• BreathID Multi-center HCV Liver Breath Test Study
  “Due to FDA comments, protocol changed; new trial will be proposed shortly” (74% match in meaning)
• Continued Access Study of Adefovir Dipivoxil (ADV) for Patients w/Chronic HBV Infection.
  “The study stopped due to marketing approval by the FDA.” (74% match in meaning)
• Safety, Tolerability, Efficacy and Dose-response of GSK2831781 in Ulcerative Colitis
  “The trial was stopped based on the assessment of clinical data.” (74% match in meaning)
• Medication Use Among American Indians Adults
  “The study has not been stopped. The study does not qualify as a clinical trial so it was withdrawn from clinicaltrials.gov.” (73% match in meaning)

Look deeper

• The official registry record (the source of truth)
• Record history: every change the sponsor made
• Open it in the database

Everything here comes from the current ClinicalTrials.gov record. The timeline uses the record’s dates; dates marked planned are the sponsor’s plans. The cause of death is an automatic, unverified label. This is research information, not medical advice.