Autopsy report · NCT03893565

Safety, Tolerability, Efficacy and Dose-response of GSK2831781 in Ulcerative Colitis

“The trial was stopped based on the assessment of clinical data.”

The sponsor’s own words in the registry.

Life of this trial

• Registered 1 month before it started.
• Ran for about 2 years before it stopped.
• 104 participants enrolled.
• Results were posted on the registry 11 months after it ended.

Vital statistics

Status

Terminated

Phase

Phase 2

Sponsor

GlaxoSmithKline

Sponsor type

Industry

Conditions

Colitis, Ulcerative

Interventions

GSK2831781 - Double Blind Phase; Placebo; GSK2831781 - Open Label phase

Participants

104

Sites

61

Countries

Bulgaria, Czechia, Estonia, France, India, Japan, Netherlands, Poland, Russia, Serbia, Slovakia, South Africa and more

Trials that died the same way

• To Assess the Safety, Tolerability and Pharmacokinetics of ACH-000029 in Healthy Subjects
  “Based on the unblinded clinical data, the trial was terminated.” (81% match in meaning)
• Study of a Melanoma Vaccine in Stage IIb, IIc, and III Melanoma Patients
  “After interim analysis the study was halted to redesign a pivotal trial.” (79% match in meaning)
• Medication Use Among American Indians Adults
  “The study has not been stopped. The study does not qualify as a clinical trial so it was withdrawn from clinicaltrials.gov.” (78% match in meaning)
• Phase II Study of TAEST16001 in Soft Tissue Sarcoma
  “The study was terminated due to initiation of a new clinical trial with an updated study design.” (75% match in meaning)
• Neoadjuvant Lu-PSMA Radioligand Therapy and Ipilimumab in Men With Very High-risk Prostate Cancer
  “The clinical trial has been terminated due to the revocation of funding. Although one subject was enrolled, the participant withdrew prior to receiving any treatment. No trial-related procedures generating evaluable clinical data were performed.” (75% match in meaning)

Look deeper

• The official registry record (the source of truth)
• Record history: every change the sponsor made
• Open it in the database

Everything here comes from the current ClinicalTrials.gov record. The timeline uses the record’s dates; dates marked planned are the sponsor’s plans. The cause of death is an automatic, unverified label. This is research information, not medical advice.