Autopsy report · NCT06374797

A Study of Auxora in Patients With AKI and Injurious Lung "Crosstalk"

“The study was stopped due to imbalance in randomization stratification of severe patients.”

The sponsor’s own words in the registry.

Life of this trial

• Registered 3 months before it started.
• Ran for about 1 year 9 months before it stopped.
• 122 participants enrolled.
• No results are posted on the registry.

Vital statistics

Status

Terminated

Phase

Phase 2

Sponsor

CalciMedica, Inc.

Sponsor type

Industry

Conditions

Acute Kidney Injury

Interventions

Auxora; Placebo

Participants

122

Sites

33

Countries

United States

Trials that died the same way

• Saracatinib in Treating Patients With Prostate Cancer
  “Per protocol, study was terminated due to low rate of randomized patients.” (64% match in meaning)
• Prolonged Exposure to Doxorubicin in Patients With Glioblastoma Multiforme and Diffuse Intrinsic Pontine Glioma
  “Study was terminated due to high heterogeneity of enrolled patients” (61% match in meaning)
• Assessment of Artificial Intelligence Algorithms for ROTEM
  “The study was stopped because it was considered unlikely that the required number of patients could be prospectively recruited across the participating study centers.” (59% match in meaning)
• Prevention Trial: Immune-tolerance With Alum-GAD (Diamyd) and Vitamin D3 to Children With Multiple Islet Autoantibodies
  “The study was interrupted early and terminated when only 26 out of 80 patients were enrolled due to new clinical study results indicating that the current study would not be informative.” (59% match in meaning)
• Adjuvant Chemotherapy With S-1 Plus Oxaliplatin Versus S-1 Alone in Locally Advanced Gastric Cancer
  “The number of patients enrolled was much less than expected” (59% match in meaning)

Look deeper

• The official registry record (the source of truth)
• Record history: every change the sponsor made
• Open it in the database

Everything here comes from the current ClinicalTrials.gov record. The timeline uses the record’s dates; dates marked planned are the sponsor’s plans. The cause of death is an automatic, unverified label. This is research information, not medical advice.