Autopsy report · NCT02758366

Prolonged Exposure to Doxorubicin in Patients With Glioblastoma Multiforme and Diffuse Intrinsic Pontine Glioma

“Study was terminated due to high heterogeneity of enrolled patients”

The sponsor’s own words in the registry.

Life of this trial

• Registered 2 months after it had already started.
• Ran for about 3 years 11 months before it stopped.
• 21 participants enrolled.
• No results are posted on the registry.

Vital statistics

Status

Terminated

Phase

Phase 2

Sponsor

Meyer Children's Hospital IRCCS

Sponsor type

University, hospital or other

Conditions

Glioblastoma (GBM); DIPG; Brainstem Glioma, Pediatric; Diffuse Spinal Glioma; Bilateral Thalamic Glioma; Gliomatosis Cerebri

Interventions

Doxorubicin

Participants

21

Sites

1

Countries

Italy

Trials that died the same way

• Alvimopan Use in Polytraumatized Patients
  “This study was terminated due to failure to enroll, a low volume of patients met criteria.” (85% match in meaning)
• GW786034 in Patients With Non Small Cell Lung Cancer 3rd Line
  “Study was terminated due to positive results seen in statistical analysis. Adequate patient enrollment was achieved.” (84% match in meaning)
• The Effect on Mucosal Healing With Pentasa Sachet in Mild to Moderate Active "Drug: Crohn's Disease"
  “Study terminated due to lack of eligible patients” (84% match in meaning)
• Assessment of the Effect of Tegaserod (2 mg Tid and 6 mg Tid) on Dyspeptic Symptoms in Diabetic Patients With Symptoms of Diabetic Gastropathy
  “This study was terminated early in April 2005 due to low patient enrollment” (83% match in meaning)
• Real-world Clinical Patterns Of Care And Outcomes Among AfME mRCC Patients Receiving Sunitinib as First Line Therapy.
  “The study was terminated early due to the inability to recruit the planned number of patients” (82% match in meaning)

Look deeper

• The official registry record (the source of truth)
• Record history: every change the sponsor made
• Open it in the database

Everything here comes from the current ClinicalTrials.gov record. The timeline uses the record’s dates; dates marked planned are the sponsor’s plans. The cause of death is an automatic, unverified label. This is research information, not medical advice.