Autopsy report · NCT06162663

Double-blind Randomized Controlled Trial Comparing Suvorexant 20 mg to Placebo for Treatment of Insomnia in Cancer Survivors

“Terminated early due to insufficient accrual to meet prespecified statistical analysis requirements.”

The sponsor’s own words in the registry.

Life of this trial

• Registered 10 months before it started.
• Ran for about 1 year 5 months before it stopped.
• 6 participants enrolled.
• Results were posted on the registry 6 months after it ended.

Vital statistics

Status

Terminated

Phase

Phase 4

Sponsor

Medical University of South Carolina

Sponsor type

University, hospital or other

Conditions

Breast Cancer; Insomnia

Interventions

Suvorexant Tablets; Placebo Control

Participants

6

Sites

1

Countries

United States

Trials that died the same way

• Anti-gp100 Cells Plus ALVAC gp100 Vaccine to Treat Advanced Melanoma
  “The study was terminated due to low accrual.” (67% match in meaning)
• Roux-en-Y Gastric Bypass Versus Loop Gastrojejunostomy for Malignant Gastric Outlet Obstruction
  “The study was terminated early due to poor participant accrual, resulting in inadequate enrollment to support the planned analysis and study endpoints.” (66% match in meaning)
• Safety and Efficacy of Melatonin in Patients With Multiple Progressive Primary Sclerosis
  “Early termination due to operational feasibility reasons, resulting from a slow recruitment rate and logistical and financial difficulties that prevent reaching the planned sample size within the study schedule.” (66% match in meaning)
• CAR T Cell Receptor Immunotherapy Targeting Mesothelin for Patients With Metastatic Cancer
  “Study terminated due to slow/insufficient accrual.” (66% match in meaning)
• Trial of Combination ABI-007, Carboplatin, and Gemcitabine for First Line Treatment of Advanced Urothelial Cancer
  “Terminated prematurely due to low accrual.” (65% match in meaning)

Look deeper

• The official registry record (the source of truth)
• Record history: every change the sponsor made
• Open it in the database

Everything here comes from the current ClinicalTrials.gov record. The timeline uses the record’s dates; dates marked planned are the sponsor’s plans. The cause of death is an automatic, unverified label. This is research information, not medical advice.