Autopsy report · NCT05986422

Methylprednisolone in Patients With Cognitive Deficits in Post-COVID-19 Syndrome (PCS)

“Following a recommendation from the Data Safety Monitoring Board (DSMB).”

The sponsor’s own words in the registry.

Life of this trial

• Registered 2 months before it started.
• Ran for about 2 years 5 months before it stopped.
• 96 participants enrolled.
• No results are posted on the registry.

Vital statistics

Status

Terminated

Phase

Phase 2

Sponsor

Charite University, Berlin, Germany

Sponsor type

University, hospital or other

Conditions

Post-COVID-19 Syndrome

Interventions

Methylprednisolone

Participants

96

Sites

1

Countries

Germany

Trials that died the same way

• High Resolution Imaging of Cerebral Vasculature by Functional Micro-Doppler Sonography During Brain Surgery
  “recommandation of the Data Safety monitoring Board” (77% match in meaning)
• Daily Isoniazid to Prevent Tuberculosis in Infants Born to Mothers With HIV
  “Data Safety Monitoring Board (DSMB) recommended stopping study due to futility” (74% match in meaning)
• A Placebo-Controlled Study of Saracatinib (AZD0530) in Patients With Recurrent Osteosarcoma Localized to the Lung
  “The Data Safety Monitoring Board (DSMB) recommended study termination for slow accrual and futility.” (73% match in meaning)
• Non-vitamin K Antagonist Oral Anticoagulants in Patients With Atrial High Rate Episodes
  “following a recommendation from the data safety and monitoring board due to safety concerns and a tendency towards futility.” (72% match in meaning)
• The Efficacy of Enteric-coated Mycophenolate Sodium (EC-MPS) (Myfortic) in The Treatment of Relapse or Resistant Proliferative Lupus Nephritis
  “Data Safety Monitoring Board concerning of the participants' safety” (67% match in meaning)

Look deeper

• The official registry record (the source of truth)
• Record history: every change the sponsor made
• Open it in the database

Everything here comes from the current ClinicalTrials.gov record. The timeline uses the record’s dates; dates marked planned are the sponsor’s plans. The cause of death is an automatic, unverified label. This is research information, not medical advice.