Autopsy report · NCT05938725

KYSA-1: A Study of Anti-CD19 Chimeric Antigen Receptor T-Cell (CD19 CAR T) Therapy, in Subjects With Refractory Lupus Nephritis

“Study discontinued due to sponsor decision.”

The sponsor’s own words in the registry.

Life of this trial

• Registered 7 months before it started.
• Ran for about 3 years 1 month before it stopped.
• 6 participants enrolled.
• No results are posted on the registry.

Vital statistics

Status

Terminated

Phase

Phase 1, Phase 2

Sponsor

Kyverna Therapeutics

Sponsor type

Industry

Conditions

Lupus Nephritis; Lupus Nephritis - World Health Organization (WHO) Class III; Lupus Nephritis - WHO Class IV

Interventions

KYV-101 anti-CD19 CAR-T cell therapy; Standard lymphodepletion regimen

Participants

6

Sites

6

Countries

United States

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  “Study was cancelled by Sponsor.” (86% match in meaning)
• Pravastatin Intervention to Delay Hepatocellular Carcinoma Recurrence
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  “Study discontinued due to futility.” (84% match in meaning)

Look deeper

• The official registry record (the source of truth)
• Record history: every change the sponsor made
• Open it in the database

Everything here comes from the current ClinicalTrials.gov record. The timeline uses the record’s dates; dates marked planned are the sponsor’s plans. The cause of death is an automatic, unverified label. This is research information, not medical advice.