Autopsy report · NCT04778397

Study of Magrolimab in Combination With Azacitidine Versus Physician's Choice of Venetoclax in Combination With Azacitidine or Intensive Chemotherapy in Patients With TP53 Mutant Acute Myeloid Leukemia That Have Not Been Treated

“Study discontinued due to futility.”

The sponsor’s own words in the registry.

Life of this trial

• Registered 4 months before it started.
• Ran for about 2 years 9 months before it stopped.
• 258 participants enrolled.
• Results were posted on the registry 10 months after it ended.

Vital statistics

Status

Terminated

Phase

Phase 3

Sponsor

Gilead Sciences

Sponsor type

Industry

Conditions

Acute Myeloid Leukemia

Interventions

Magrolimab; Venetoclax; Azacitidine; Cytarabine; Daunorubicin; Idarubicin

Participants

258

Sites

156

Countries

Australia, Austria, Belgium, Canada, Denmark, France, Germany, Hong Kong, Italy, Japan, Spain, Sweden and more

Trials that died the same way

• Magrolimab + Azacitidine Versus Azacitidine + Placebo in Untreated Participants With Myelodysplastic Syndrome (MDS)
  “Study discontinued due to futility based on a planned analysis” (89% match in meaning)
• Pravastatin Intervention to Delay Hepatocellular Carcinoma Recurrence
  “Study discontinued due to low accrual.” (86% match in meaning)
• Comparison Between Radiofrequency and Balloon Compression in the Treatment of Idiopathic Trigeminal Neuralgia
  “Study halted due to futility” (85% match in meaning)
• Study of Nintedanib and Chemotherapy for Advanced Pancreatic Cancer
  “The study was terminated due to futility and lack of future funding” (85% match in meaning)
• Prospective Comparison of Revolve™ and AuraGen 123 With AuraClens™ in Autologous Fat Grafting to the Breast
  “Study discontinued due to lack of subject follow-up.” (85% match in meaning)

Look deeper

• The official registry record (the source of truth)
• Record history: every change the sponsor made
• Open it in the database

Everything here comes from the current ClinicalTrials.gov record. The timeline uses the record’s dates; dates marked planned are the sponsor’s plans. The cause of death is an automatic, unverified label. This is research information, not medical advice.