Autopsy report · NCT05490186

Function, Pain, and Alignment Following Knee Replacement for the Treatment of Osteoarthritis

“The study was prematurely terminated due to a long pause in study activities and significant missing participant data.”

The sponsor’s own words in the registry.

Life of this trial

• Ran for about 2 years 3 months before it stopped.
• 261 participants enrolled.
• No results are posted on the registry.

Vital statistics

Status

Terminated

Phase

Na

Sponsor

North York General Hospital

Sponsor type

University, hospital or other

Conditions

Knee Replacement, Total; Pain, Postoperative; Functional Independence

Interventions

Total Knee Replacement

Participants

261

Sites

1

Countries

Canada

Trials that died the same way

• Leronlimab (PRO 140) Combined With Carboplatin in Patients With Cytokine Chemokine Receptor 5 Positive (CCR5+) mTNBC
  “Study terminated prematurely due to business reasons. Participants are no longer examined or receiving intervention.” (83% match in meaning)
• Starting the Conversation
  “The study was terminated due to a small number of study participants.” (80% match in meaning)
• Sevoflurane in Chronic Obstructive Pulmonary Disease Exacerbation
  “Study halted prematurely and will not resume; participants are no longer being examined or receiving intervention The study was terminated prematurely due to inclusion difficulties” (78% match in meaning)
• Study to Evaluate the Efficacy and Safety of Moxifloxacin Versus Amoxicillin/Clavulanate in the Treatment of Acute Bacterial Rhinosinusitis
  “The study was prematurely terminated due to slow enrollment beyond the planned study timelines.” (77% match in meaning)
• A Comparison of Surgical Preparations and Wound Infection Rates for Elective Cesarean Sections
  “Study was stopped following interim analysis.” (77% match in meaning)

Look deeper

• The official registry record (the source of truth)
• Record history: every change the sponsor made
• Open it in the database

Everything here comes from the current ClinicalTrials.gov record. The timeline uses the record’s dates; dates marked planned are the sponsor’s plans. The cause of death is an automatic, unverified label. This is research information, not medical advice.